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  • Graduate Student
  • Lab assistant
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  • Physician
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  • Deputy Director of National Reference Center
  • Director of Center
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About

Sébastien Brier  hold an Engineer degree in Biology from Polytech Clermont-Ferrand, and received his Ph.D. in Structural Proteomics at the group of Dr. Eric Forest in 2005 in Grenoble, developing HDX-MS approaches to study the binding of small inhibitors to human mitotic kinesins. He completed postdoctoral work at the Barnett Institute of Chemical Biology in Boston in the group of Professor John. R. Engen, and at the CNRS in Paris, France. In 2009, He was appointed research investigator at Novartis Vaccines and Diagnostics in Siena, Italy, to create a HDX-MS platform dedicated to the structural analysis of protein vaccines . In Autumn 2012 He came back to Paris as a research associate in Structural Proteomics at Stallergenes, working on the use of the HDX technology to map IgE epitopes on natural allergens to optimize the design of recombinant vaccines. Currently, Sébastien has implemented and manages the HDX-MS platform at Institut Pasteur in Paris working on membrane-associated proteins involved in infectious disease.

Events

HDX-MS/NMR DAY

Room: Amphitheater François Jacob – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2017-03-16 09:00:00 2017-03-16 18:00:00 Europe/Paris HDX-MS/NMR DAY Dear Colleagues, We are pleased to invite you to attend our upcoming Hydrogen Deuterium eXchange Day (HDX-Day) that will be held at the Institut Pasteur, Paris, on Thursday March 16th 2017. The aim of this […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Projects

CV

(EN)

 

  • Nov. 2013 to present: Permanent Research Engineer in Structural Proteomics (HDX-MS) – Structural Mass Spectrometry and Proteomics Unit – Institut Pasteur – Paris – France
  • 2011-2013: Permanent Research Engineer in Structural Proteomics -Stallergenes – Antony – France
  • 2009-2011: Research Associate – Nathalie Norais Group – Novartis Vaccines and Diagnostics – Siena – Italy
  • 2007-2008: Postdoctoral fellow – Daniel Regis Group – CNRS – Univeristé Evry Val d’Essonne – France
  • 2006-2007: Postdoctoral Research Associate – Prof. John R. Engen Group – The Barnett Institute – Northeastern University – Boston – USA
  • 2005: Ph.D in Structural Biology and NanoBiology (C.E.A / CNRS) – Eric Forest Group – Institut de Biologie Stucturale J.P.Ebel – Grenoble – France.
  • 2002: D.E.A Génétique et Physiologie Moléculaires – Université de Clermont-Ferrand II – France
  • 2002: Engineer Degree in Biology (Polytech Clermont Ferrand (C/U/S/T)) – Clermont Ferrand – France
  • 1999: BSc (HONS) Applied Biochemistry with second class honour, grade 1– University of Central Lancashire – Preston – United Kingdom

 

Publications