Cytoskeleton and Mechanobiology projects
Until now, the role of actin in cell migration has been extensively studied, but much less is known about the role of microtubules and Intermediate Filaments(IFs) (Dutour-Provenzano and Etienne-Manneville, 2021, 34033784; Etienne-Manneville, 2018, 30059630). […]
Covid19 related project
Role of the E-protein in intracellular viral behavior (Batiste Boëda, INSERM) The coronavius genome encodes four major structural proteins: the spike (S) protein, nucleocapsid (N) protein, membrane (M) protein, and the envelope (E) protein. […]
Cell Polarity projects
What are the central components of polarity pathways ? Are they affected during gliomagenesis? Using astrocyte directed migration as a model system, we have identified evolutionary conserved polarity signals that control cell polarity […]
Reorganization of cytoskeletal elements and cell migration – Perturbation of the regulation of cytoskeletal networks in glioblastoma cells
How are cytoskeletal elements reorganized to promote cell migration? Is the regulation of the cytoskeletal networks perturbed in glioblastoma cells? We have shown that the three main cytoskeletal networks, microfilaments, microtubules and intermediate filaments […]
Determining the central components of polarity pathways and their affection during gliomagenesis
What are the central components of polarity pathways ? Are they affected during gliomagenesis? Using astrocyte directed migration as a model system, we have identified evolutionary conserved polarity signals that control cell polarity and […]
Role and dynamics of cell-cell interactions during cell polarization and collective directed migration
What are the role and the dynamics of cell-cell interactions during cell polarization and collective directed migration? How loss of cellular interactions affects the migratory behavior of glioblastoma cells? We have shown that the […]
2021Multiscale rheology of glioma cells., Biomaterials 2021 May; 275(): 120903.
2021Intermediate filaments., Curr Biol 2021 May; 31(10): R522-R529.
2020Cytoskeletal Crosstalk in Cell Migration., Trends Cell Biol. 2020 Jul; (): .
2020Intermediate filaments against actomyosin: the david and goliath of cell migration., Curr. Opin. Cell Biol. 2020 Jul; 66(): 79-88.
2020P120catenin tuning of VE-cadherin endocytosis controls collective cell behavior during angiogenesis., J. Cell Biol. 2020 May; 219(5): .
2020A toxic palmitoylation of Cdc42 enhances NF-κB signaling and drives a severe autoinflammatory syndrome., J. Allergy Clin. Immunol. 2020 Apr; (): .
2020Cell polarity inside-out, Curr. Opin. Cell Biol. 2020 Feb;62:iii-iv.
2019Multicellular scale front-to-rear polarity in collective migration, Curr. Opin. Cell Biol. 2019 Nov;62:114-122.
2019Microtubules at focal adhesions – a double-edged sword, J. Cell. Sci. 2019 Oct;132(19).
2019Microtubule acetylation but not detyrosination promotes focal adhesion dynamics and astrocyte migration, J. Cell. Sci. 2019 Apr;132(7).
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