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© A-M. Pais-Correia, M-I. Thoulouze, A. Alcover, A. Gessain
Mise en évidence de structures de type "biofilm ", formées par le rétrovirus HTLV-1 générés par des cellules infectées (cellules du haut), qui ont été transmis à un autre lymphocyte (cellule du bas). Micrographie en microscopie électronique à balayage. Image colorisée.

About

Patricia Jeannin is graduated in virology (Master of science in medical virology)

She work in Pasteur Institute since 2003.

Patricia Jeannin takes part to the diagnostic of flu viruses in influenza CNR (Immunology : ELISA… Molecular Biology :PCR, Sequencing… Virology : viruses culture, virus production on eggs… and Cell culture technologies).

She also works on HIV controlors to search for immunological markers. (Immunology : ELISpot, FACS… and Cell culture technologies.)

Actually, Patricia is involved in collaborative research between the Necker Enfants-Malades Hospital (Adult Hematology Service and Onco-Hematology Laboratory) and the Institut Pasteur (Epidemiology and Pathophysiology of Oncogenic Viruses Unit). The aim of this study is to develop PDX lines in mice for ATLLs, in order to study the mechanisms of leukemogenesis linked to infection by the HTLV-1 virus, and to evaluate the effectiveness of new protocols / molecules to therapeutic aim.

She is too associated to researches on different biological barriers (intestinal and blood brain barrier) to study the physiopathology of HTLV (Molecular Biology : PCR, Blot, Cloning… Immunology : ELISA… Cell culture : compatimented system, filter system….).

Lastly, she is the hygien and security correspondant of EPVO unit.

Projects

Project
Ongoing
3 Members

Alteration of exosomes upon HTLV infection

Philippe Afonso (PI)
Project
Ongoing
6 Members

Interactions between Human T lymphotropic virus type 1 (HTLV-1) and the blood-brain barrier

Philippe Afonso (PI)

Human T-lymphotropic virus type 1 (HTLV-1) is the etiological agent of a slowly progressive neurodegenerative disease, HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). This disease develops upon infiltration of HTLV-1-infected lymphocytes into the central nervous system, […]

Publications

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