Mélanie Legrand is a permanent scientist in the Fungal Biology and Pathogenicity Unit. Mélanie Legrand has gained her Master degree at the University of Minnesota working on mating in the human fungal pathogens Candida albicans and Candida dubliniensis in the laboratory of Prof. Paul Magee. She has completed her PhD degree working on DNA repair in Candida albicans with Dr. David Kirkpatrick at the University of Minnesota. She joined the Unit of Fungal Biology and Pathogenicity Unit headed by Prof. Christophe d’Enfert at the Institut Pasteur to study the molecular mechanisms involved in maintenance of genome integrity in Candida albicans. She obtained a permanent INRA position in 2010.
She is interested in Candida albicans’ general biology, genome dynamics and mating. Presently, she is leading a project on the identification of regulators of « Loss of Heterozygosity » in C. albicans. She also contributes to the C. albicans ORFeome project.
Candida albicans genomic diversity and its underlying mechanisms
Following our introduction of Multi-Locus Sequence Typing (MLST) as the state-of-the-art methodology for molecular epidemiology studies of C. albicans, the Fungal Biology and Pathogenicity Unit at Institut Pasteur is now progressing into population genomics […]