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© Lucie Peduto, Institut Pasteur
Stroma du ganglion lymphatique

About

Lucie Peduto obtained her PhD in Tumor Biology at the University of Lausanne/CHUV (Switzerland) and Ecole Pratique des Hautes Etudes in Paris. She joined the lab of Carl Blobel at Sloan-Kettering Institute (New York) for a postdoctoral training on the role of ADAMs proteins in cancer, and became faculty member of the Department of Immunology at Institut Pasteur (Paris) in 2010, where she is directing since 2016 a Research Unit focusing on the role of the stromal microenvironment in cancer and fibrosis. Lucie Peduto is currently Associate Professor (Directeur de Recherche) at Institut Pasteur, and holds an accreditation as research director from the University Paris Descartes. She has received support from La Ligue contre le Cancer, l’ARC, l’ANR, FRM and was awarded an ERC Consolidator Grant (European Research Council) for her work on cancer and fibrosis.

Projects

Project
Completed
16 Members

Oncobiomics – THE (heterogenity tumor ecosystem)

Marc Monot (PI)

The Oncobiomics project is conducted in the HTE (heterogenity tumor ecosystem) national program launched by the cancer nation institute (Inca) in the third national cancer plan 2014-2019. It’s a consortium project involving 8 teams […]
Project
Ongoing
4 Members

Role of nutrition and the microenvironment in cancer development

Lucie Peduto (PI)

Cancer is increasingly recognized as a multifactorial disease, resulting from a dysregulated communication between different cell types of the tumor microenvironment, including cancer cells, infiltrating immune cells and resident stromal cells, altogether modulated by […]
Project
Ongoing
5 Members

ERC-CoG-PERIF Perivascular cells at the crossroads of inflammation, regeneration and fibrosis

Lucie Peduto (PI)

The survival of organisms requires the ability to repair tissues upon injury, as well as, after birth, to fight foreign invaders that may have contaminated the wound. This last function is mediated by a […]
Project
Completed
10 Members

Think tank: Cancer

Ludovic Deriano (PI)

The malignant transformation of cells translates into a major worldwide health, social and economic burden. Efforts to define the etiology of cancer, along with the development of new therapeutic approaches to treat them, would […]
Project
Ongoing
4 Members

The stromal microenvironment in intestinal homeostasis / immunity

Lucie Peduto (PI)

The intestine contains abundant and heterogeneous populations of stromal cells. Using several genetic approaches as well as intestinal organoid models, we are investigating the role of the stromal microenvironment in intestinal homeostasis and repair,  […]
Project
Ongoing
3 Members

The tumor stromal microenvironment

Lucie Peduto (PI)

Tumor progression, invasion and ultimately metastasis result from interactions between cancer cells and their supporting stromal microenvironment. The tumor stromal microenvironment share many similarities with fibrotic stroma and comprises extracellular matrix components, as well […]

Publications

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