Jerome Gros obtained his PhD in 2006 from the University of Marseille-Luminy in France, in the field of Developmental Biology. He then moved Boston, USA as a postdoctoral fellow in the laboratory of Cliff Tabin in the department of Genetics at Harvard Medical School. In 2012, Dr Gros became an Assistant Professor of Developmental and Stem Cell Biology at the Institut Pasteur in Paris, France where his research focuses on the imaging and regulation of the cellular events that shape the early vertebrate embryo.
Of cavefish and cavemen. What can we learn from blind, fat fish to keep us healthy. By Nicolas Rohner, Stowers Institute for Medical Research, Kansas City, USA
“Imaging and Regulation of the Cellular Dynamics Driving Vertebrate Limb Formation”. HDR defense, Jérôme Gros, Head of the Morphogenesis Regulation in Higher Vertebrates group.
Developing genomic and molecular genetic resources in quails to investigate dynamic morphogenesis in higher vertebrates.
Embryonic development requires that the behaviour of thousands of cells be finely orchestrated in concert with signalling pathways. While much work has focused on the genetic and transcriptional control of morphogenesis, how cell dynamics […]
HFSP- 2015- Mechanical control of progenitor cell renewal and differentiation during vertebrate limb formation
During embryonic development, both biochemical and mechanical cues establish the cell differentiation patterns that shape tissues and organs. While the role of signaling molecules has been widely studied, how mechanical forces affect progenitor cell […]
Limb defects, which are amongst the most frequent congenital malformations in humans, are the result of deviation in normal developmental program deployment affecting limb specification, initiation or patterning. In most cases the mechanisms underlying […]
2014A relative shift in cloacal location repositions external genitalia in amniote evolution, Nature 2014 Dec;516(7531):391-4.
2014Vertebrate limb bud formation is initiated by localized epithelial-to-mesenchymal transition, Science 2014 Mar;343(6176):1253-6.
2010WNT5A/JNK and FGF/MAPK pathways regulate the cellular events shaping the vertebrate limb bud, Curr. Biol. 2010 Nov;20(22):1993-2002.
2009[Cell movements break left/right symmetry in the chick embryo], Med Sci (Paris) 2009 Oct;25(10):777-9.
2009The timing of emergence of muscle progenitors is controlled by an FGF/ERK/SNAIL1 pathway, Dev. Biol. 2009 Sep;333(2):229-37.
2009Cell movements at Hensen’s node establish left/right asymmetric gene expression in the chick, Science 2009 May;324(5929):941-4.
2008WNT11 acts as a directional cue to organize the elongation of early muscle fibres, Nature 2009 Jan;457(7229):589-93.
2008The chirality of gut rotation derives from left-right asymmetric changes in the architecture of the dorsal mesentery, Dev. Cell 2008 Jul;15(1):134-45.
2008Myostatin promotes the terminal differentiation of embryonic muscle progenitors, Genes Dev. 2008 Mar;22(5):668-81.
2005[A common somitic origin for embryonic muscle progenitors], Med Sci (Paris) 2005 Nov;21(11):915-7.
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