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  • Director of Center
  • Director of Department
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© Institut Pasteur/Antoinette Ryter
Coupe de Mycobacterium bovis ou bacille de Calmette et Guérin (BCG). Souche atténuée de bacille vivant, à l'origine du vaccin antituberculeux délivré par voie intradermique ou scarifications (Grossissement X 70000). Image colorisée.

Projects

Project
Completed
10 Members

Think tank: Cancer

Ludovic Deriano (PI)

The malignant transformation of cells translates into a major worldwide health, social and economic burden. Efforts to define the etiology of cancer, along with the development of new therapeutic approaches to treat them, would […]
Project
Ongoing
3 Members

Advanced Immunization Technologies (ADITEC)

Claude Leclerc (PI)

We are member of the ADITEC Consortium, a collaborative research programme that aims to accelerate the development of novel and powerful immunisation technologies for the next generation of human vaccines. Scientists from 13 countries […]
Project
Ongoing
8 Members

Clinical development of cancer vaccines

Claude Leclerc (PI)

CyaA-based therapeutic cancer vaccines Based on our discovery that a bacterial protein, the adenylate cyclase (CyaA), binds to dendritic cells (DCs), we have developed a highly efficient vector capable of targeting a wide range […]
Project
Ongoing
8 Members

Therapeutic potential of mycolactone and synthetic surrogates

Caroline Demangel (PI)

Whether released by bacteria infecting the skin or injected via the subcutaneous route, mycolactone was found to diffuse into the leukocytes of peripheral blood and lymphoid organs. With this distribution profile, the unique effects […]
Project
Ongoing
7 Members

Tumor immunity and preclinical development of cancer vaccines

Claude Leclerc (PI)

Human Papillomaviruses (HPV) are the major cause of human cervical cancer. We have developed a therapeutic tumor vaccine, the CyaA-E7 vaccine, that can induce specific responses against the HPV E7 oncoprotein and eliminate E7 […]

Publications

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