Born and raised in Madrid (Spain), I moved to Paris to study at the Ecole Normale Supérieure. I earned my PhD in Physiology and Pathophysiology at the Université Pierre et Marie Curie-Paris 6 in 2009. During my doctoral training at the College de France, I investigated the formation and maturation of blood vessels during development and in ischemic diseases. As a postdoctoral fellow, I joined Frederic Geissmann’s lab, in the Centre of Molecular and Cellular Biology of Inflammation (CMCBI, King’s College London, UK), where I studied the development of macrophages. I was recruited as a Group leader in the Development and Stem Cell Biology Department at the Institut Pasteur where I head the G5 laboratory “Macrophages and endothelial cells”.
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About
Transversal Projects
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CV
Recipient of the Prix Claude Paoletti 2015
Recipient of the FSER young investigator award 2016
Publications
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2024Extraembryonic hematopoietic lineages-to macrophages and beyond., Exp Hematol 2024 Aug; 136(): 104285.
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2024Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia., Elife 2024 May; 12(): .
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2024Early-wave macrophages control late hematopoiesis., Dev Cell 2024 May; 59(10): 1284-1301.e8.
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2022Erythro-myeloid progenitor origin of Hofbauer cells in the early mouse placenta., Development 2022 Apr; 149(8): .
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2021Megakaryocyte production is sustained by direct differentiation from erythromyeloid progenitors in the yolk sac until midgestation., Immunity 2021 May; (): .
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2021Yolk sac, but not hematopoietic stem cell-derived progenitors, sustain erythropoiesis throughout murine embryonic life., J Exp Med 2021 04; 218(4): .
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2020Functionally distinct resident macrophage subsets differentially shape responses to infection in the bladder., Sci Adv 2020 Nov; 6(48): .
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2020Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation., Nat Commun 2020 09; 11(1): 4549.
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2020A wave of bipotent T/ILC-restricted progenitors shapes the embryonic thymus microenvironment in a time-dependent manner., Blood 2021 Feb 25; 137(8): 1024-1036.
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2017Identification Of Erythromyeloid Progenitors And Their Progeny In The Mouse Embryo By Flow Cytometry, J Vis Exp 2017 Jul;(125).
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