Born and raised in Madrid (Spain), I moved to Paris to study at the Ecole Normale Supérieure. I earned my PhD in Physiology and Pathophysiology at the Université Pierre et Marie Curie-Paris 6 in 2009. During my doctoral training at the College de France, I investigated the formation and maturation of blood vessels during development and in ischemic diseases. As a postdoctoral fellow, I joined Frederic Geissmann’s lab, in the Centre of Molecular and Cellular Biology of Inflammation (CMCBI, King’s College London, UK), where I studied the development of macrophages. I was recruited as a Group leader in the Development and Stem Cell Biology Department at the Institut Pasteur where I head the G5 laboratory “Macrophages and endothelial cells”.
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Seminar by Thomas Wynn, Head of the Early Discovery, Inflammation and Immunology unit, Pfizer Worldwide R&D
Building: Monod – Room: Amphi Monod – Address: 25 Rue du Docteur Roux, Paris, France
2018-05-16 11:00:00 2018-05-16 00:00:00 Europe/Paris Seminar by Thomas Wynn, Head of the Early Discovery, Inflammation and Immunology unit, Pfizer Worldwide R&D “Type II immunity in tissue repair, regeneration and fibrosis” 25 Rue du Docteur Roux, Paris, France
Recipient of the Prix Claude Paoletti 2015
Recipient of the FSER young investigator award 2016
2017Identification Of Erythromyeloid Progenitors And Their Progeny In The Mouse Embryo By Flow Cytometry, J Vis Exp 2017 Jul;(125).
2016The Heterogeneity of Ly6C(hi) Monocytes Controls Their Differentiation into iNOS(+) Macrophages or Monocyte-Derived Dendritic Cells, Immunity 2016 Dec;45(6):1205-1218.
2016ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2, J. Pathol. 2016 Aug;.
2016Development and function of tissue resident macrophages in mice, Semin. Immunol. 2015 Dec;27(6):369-78.
2016The development and maintenance of resident macrophages, Nature Immunology 17, 2–8 (2016).
2015The development and maintenance of resident macrophages, Nat. Immunol. 2015 Dec;17(1):2-8.
2015The Origin of Tissue-Resident Macrophages: When an Erythro-myeloid Progenitor Is an Erythro-myeloid Progenitor, Immunity 2015 Dec;43(6):1023-4.
2014Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors, Nature 2015 Feb;518(7540):547-51.
2014Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice, Nat. Immunol. 2014 Oct;15(10):929-37.
2014Cancer immunology. Identifying the infiltrators, Science 2014 May;344(6186):801-2.
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