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  • Veterinary
  • Visiting Scientist
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  • Deputy Head of Facility
  • Director of Center
  • Director of Department
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© Research

Projects

Project
Ongoing
7 Members

PTR 232-2019. Mechabiome. Computational imaging of the spatiotemporal distribution of forces in gut tissue: a study of the cross talk between cell mechanics, microbiome and infectious processes

Elisabeth Labruyère (PI)

Mechanical forces trigger many cellular functions and change the geometry and physical properties of a tissue. Very few studies look at the biomechanisms of invasion of microbes at tissue level. – In this project […]
Project
Ongoing
6 Members

Impact of tissue components on cell migration: adhesion strength, cell morpho-dynamics and intracellular biophysics parameters.

Elisabeth Labruyère (PI)

We aim to analyze the impact of substrates on Entamoeba histolytica mode of migration during colonic mucosa invasion using live imaging and quantitative image analysis. E. histolytica, the etiological agent of amoebiasis, is a […]
Project
Ongoing
6 Members

Impact of gut mechanical forces and 3D architecture on the intestine homeostasis during pathogen interaction and in cancer disease

Nathalie Sauvonnet (PI)

The intestine, and in particular the colon, comprising a mucus blanket, an epithelial monolayer and the lamina propria rich in immune cells, is constantly subjected to shear stress (flow) and peristaltic motion (stretching), both […]
Project
Completed
7 Members

Imaging and mathematical modelling of cell morphology and motility

Alexandre Dufour (PI)

Elucidating the mechanisms underlying cell deformation and motility is a topic of major interest in cell biology, for they are strongly involved in cell development, immune responses, cancer and infectious diseases. This projects focuses on the […]

Publications

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