Publications

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2020

Decourty L, Malabat C, Frachon E, Jacquier A, Saveanu C, Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast, biorxiv.
2019

Zhang E, Khanna V, Dacheux E, Namane A, Doyen A, Gomard M, Turcotte B, Jacquier A, Fromont-Racine M, A specialised SKI complex assists the cytoplasmic RNA exosome in the absence of direct association with ribosomes, EMBO J. 2019 07;38(14):e100640.
2019

Tesina P, Heckel E, Cheng J, Fromont-Racine M, Buschauer R, Kater L, Beatrix B, Berninghausen O, Jacquier A, Becker T, Beckmann R, Structure of the 80S ribosome-Xrn1 nuclease complex, Nat. Struct. Mol. Biol. 2019 04;26(4):275-280.
2018

Dehecq M, Decourty L, Namane A, Proux C, Kanaan J, Le Hir H, Jacquier A, Saveanu C, Nonsense-mediated mRNA decay involves two distinct Upf1-bound complexes, EMBO J. 2018 Oct;.
2018

Nevers A, Doyen A, Malabat C, Néron B, Kergrohen T, Jacquier A, Badis G, Antisense transcriptional interference mediates condition-specific gene repression in budding yeast, Nucleic Acids Res. 2018 May;.
2017

Pierre Plateau, Cosmin Saveanu, Roxane Lestini, Marc Dauplais, Laurence Decourty, Alain Jacquier, Sylvain Blanquet & Myriam Lazard, Exposure to selenomethionine causes selenocysteine misincorporation and protein aggregation in Saccharomyces cerevisiae, Sci. Rep. 2017 Mar 17;7:44761. doi: 10.1038/srep44761.
2017

Defenouillère Q, Namane A, Mouaikel J, Jacquier A, Fromont-Racine M, The ribosome-bound quality control complex remains associated to aberrant peptides during their proteasomal targeting and interacts with Tom1 to limit protein aggregation, Mol. Biol. Cell 2017 May;28(9):1165-1176.
2016

Schmidt C, Kowalinski E, Shanmuganathan V, Defenouillère Q, Braunger K, Heuer A, Pech M, Namane A, Berninghausen O, Fromont-Racine M, Jacquier A, Conti E, Becker T, Beckmann R, The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex, Science 2016 12;354(6318):1431-1433.
2016

Saveanu C, Jacquier A, How cells kill a “killer” messenger, Elife 2016;5.
2016

Defenouillère Q, Zhang E, Namane A, Mouaikel J, Jacquier A, Fromont-Racine M, Rqc1 and Ltn1 Prevent C-terminal Alanine-Threonine Tail (CAT-tail)-induced Protein Aggregation by Efficient Recruitment of Cdc48 on Stalled 60S Subunits, J. Biol. Chem. 2016 Jun;291(23):12245-53.
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Alain Jacquier

• Genetics of genomes • Genetics of Macromolecular Interactions

Projects

Translation and Ribosome rescue

Diversity and stability of eukaryotic transcripts

Genome-wide genetic screens by GIM (Genetic Interactions Mapping)

Publications