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© Laure Mancini
Neural stem cells of the zebrafish adult telencephalon visualized by confocal microscopy
Event

BDCS Department seminar by Dr. Stéphane Nédelec, Stem cells in neurodevelopment and diseases team, Institut du fer à moulin Inserm, UPMC, Paris

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
15
Jun 2018
Time
11:00:00
25 Rue du Dr Roux, Paris, France
Address
Building: Monod
Location
2018-06-15 11:00:00 2018-06-15 00:00:00 Europe/Paris BDCS Department seminar by Dr. Stéphane Nédelec, Stem cells in neurodevelopment and diseases team, Institut du fer à moulin Inserm, UPMC, Paris “Temporal construction and deconstruction of neuronal identities in development and disease: a human pluripotent stem cell perspective” Targeted differentiations of pluripotent stem cells open new avenues to study the development, evolution and disease of […] 25 Rue du Dr Roux, Paris, France Laure Bally-Cuif laure.bally-cuif@pasteur.fr

About

“Temporal construction and deconstruction of neuronal identities in development and disease: a human pluripotent stem cell perspective”

Targeted differentiations of pluripotent stem cells open new avenues to study the development, evolution and disease of the human nervous system. Using this approach, we are deciphering the mechanisms controlling the HOX-mediated temporal specification of neuronal diversity during spinal cord elongation in mouse and human. Elucidation of these developmental principles provides us with strategies to engineer specific neuronal populations to approach the molecular basis of the selective resistance or vulnerability of closely related neuronal subtypes in neurodevelopmental motor neuron diseases.

Location

Building: Monod
Address: 25 Rue du Dr Roux, Paris, France