The MOOC takes stock of tuberculosis today and the challenges posed by drug resistance and therapeutic advances.
- Registration on: https://www.fun-mooc.fr/en/courses/tuberculosis/
At the end of this course, you will be able to:
- Know about the new advances in clinical and molecular tools used in TB diagnosis, drug sensitivity testing and genome sequencing technologies.
- Decide what are the most efficient and patient-adapted treatment regimens to cure drug resistant mycobacteria.
- Be updated on the development status of new promising anti-TB agents and vaccine candidates.
Tuberculosis has been a scourge of humanity for hundreds of years. In the 18th and 19th centuries, tuberculosis was called the white plague and in some countries in Europe and the US was responsible for 20% or more of all deaths. Today, out of all infectious agents, tuberculosis remains the biggest killer, surpassing even HIV and malaria. In 2015, according to WHO, there were nearly 10.4 million new cases of tuberculosis and around 1.8 million people died from the disease, making it one of the top 10 causes of deaths worldwide.
Although there are plans to eliminate it within the next couple of decades, the incidence is currently only falling by about 1.5% per year. Part of the problem is the nature of the disease, which takes months to develop and requires months of multi-drug chemotherapy to cure. It can also stay latent for decades and then emerge to cause serious illness. Another problem, this one man-made, is the drug resistance and multi-drug resistance that make TB much harder to cure.
To provide an up-to-date overview of the disease, the Institut Pasteur has created a MOOC dedicated to Tuberculosis. This course will provide a knowledge base that goes from the basics of TB to the current state of knowledge on various aspects of tuberculosis: the clinical picture, epidemiology, pediatric TB, factors affecting susceptibility to the disease, including HIV, diabetes and human genetics, immunology, vaccines, diagnosis, current and future ways to detect drug resistance, and how to treat drug sensitive and multi-drug resistant strains. It will also discuss clinically important non-tuberculous mycobacterial infections and how to diagnose and treat them. It will present recent advances in molecular techniques for diagnosis and drug sensitivity testing, including Whole Genome Sequencing, and the new, shorter and more effective treatment regimens to cure Multi-Drug Resistant TB.
The course aims at providing a broad overview of the current state of knowledge about tuberculosis for physicians, nurses and other health and public health workers, microbiologists, pharmacists, researchers and students. It will serve as a valuable update for people working with tuberculosis, a thorough introduction for those who are new to the field and a great opportunity for all those who want to broaden their understanding of the disease.
Registration on: https://www.fun-mooc.fr/en/courses/tuberculosis/
Pôle d’enseignement Numérique