Publications
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2018Unexpected genomic and phenotypic diversity of Mycobacterium africanum Lineage 5 affects drug resistance, protein secretion and immunogenicity, Genome Biol Evol 2018 Jul;.
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2018RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection, PLoS Pathog. 2018 Jun;14(6):e1007139.
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2018Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors, Cell Rep 2018 Apr;23(4):1072-1084.
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2017Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection, Cell Reports 2017, 18, (11), 2752–2765.
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2017Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis, Mucosal Immunol 2017 Sep;10(5):1178-1189.
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2016ESX secretion systems: mycobacterial evolution to counter host immunity, Nat. Rev. Microbiol. 2016, 14(11):677-691..
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2016CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection, PLoS Pathog. 2016 Jul 28;12(7):e1005770. doi: 10.1371/journal.ppat.1005770..
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2015Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo, PLoS Pathog. 2015 Feb;11(2):e1004650.
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2013Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis, Nat. Genet. 2013 Feb;45(2):172-9.
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2012Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential, Cell Host Microbe 2012 Apr;11(4):352-63.
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