Courses
MOOC Tuberculosis
This course takes stock of tuberculosis today and the challenges posed by drug resistance and therapeutic advances. >> Sign up here << Tuberculosis has been a scourge of humanity for thousands of years. Today, […]
2022-09-06 09:00:00
2023-01-31 22:00:00
Europe/Paris
MOOC Tuberculosis
This course takes stock of tuberculosis today and the challenges posed by drug resistance and therapeutic advances. >> Sign up here << Tuberculosis has been a scourge of humanity for thousands of years. Today, […]
Institut Pasteur, Rue du Docteur Roux, Paris, France
Publications
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2022The Mycobacterium tuberculosis PhoPR virulence system regulates expression of the universal second messenger c-di-AMP and impacts vaccine safety and efficacy., Mol Ther Nucleic Acids 2022 Mar; 27(): 1235-1248.
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2020Phthiocerol Dimycocerosates From Mycobacterium tuberculosis Increase the Membrane Activity of Bacterial Effectors and Host Receptors., Front Cell Infect Microbiol 2020 ; 10(): 420.
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2020Live attenuated TB vaccines representing the three modern Mycobacterium tuberculosis lineages reveal that the Euro-American genetic background confers optimal vaccine potential, EBioMedicine 2020 Apr;55:102761.
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2020TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages, Nat Commun 2020 Feb;11(1):684.
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2019Mycobacterial virulence: impact on immunogenicity and vaccine research, F1000Res 2019;8.
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2018Unexpected genomic and phenotypic diversity of Mycobacterium africanum Lineage 5 affects drug resistance, protein secretion and immunogenicity, Genome Biol Evol 2018 Jul;.
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2018RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection, PLoS Pathog. 2018 Jun;14(6):e1007139.
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2018Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors, Cell Rep 2018 Apr;23(4):1072-1084.
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2017Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection, Cell Reports 2017, 18, (11), 2752–2765.
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2017Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis, Mucosal Immunol 2017 Sep;10(5):1178-1189.
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