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About

Statistical and Mathematical Modeling in Biological Applications — SaMMBA

Seminars are currently accessible onsite (seminar + buffet lunch) and online (link provided by email).

[It is possible to contact the organisers to be included on the mailing list]

The seminar series Statistical and Mathematical Modeling in Biological Applications (SaMMBA) features monthly lectures and discussions with leading modelers in biological sciences. Presentations are in English or French and target an interdisciplinary audience. Seminars are held on the campus of Institut Pasteur. Access is free. However, to enter the campus, one needs be pre-registered and get a badge that is obtained at the main gate in exchange of a piece of ID (passport, citizen card or driver licence). If you are planning to come from outside the campus, please contact Lulla Opatowski to have a badge ready when you arrive.

For additional information about the series, contact the organizers.

The SaMMBA seminars is currently funded by the ANRS-MIE (AC modelisation), the Inception program, and the Institut Pasteur.

We received in the past financial support in the past from the ANRS, the region Ile de France through the DIM Systèm es complexes and the DIM One health, from Inserm and the department MIA of INRA.

Former active organizers of the seminars: Virginie Supervie, Elisabeta Vergu, Romulus BrebanVittoria Colizza, Lulla Opatowski, Raphaëlle Metras & Laura Temime.

Next Lecture

Matthieu Domenech de Celles (Max Planck Institute for Infection Biology)

Title : How causal inference concepts can guide research into the effects of climate on infectious diseases

Abstract
: A pressing question resulting from global warming is how climate change will affect infectious diseases. Answering this question requires research into the effects of weather on the population dynamics of transmission and infection; elucidating these effects, however, has proven difficult due to the challenges of assessing causality from the predominantly observational data available in epidemiological research. In this talk, I will show how concepts from causal inference—the sub-field of statistics aiming at inferring causality from data—can guide that research. Through a series of case studies building on a simple transmission model with an exact causal representation, I will illustrate how such concepts can help assess study design and strategically choose a study’s location, evaluate and reduce the risk of bias, and interpret the multifaceted effects of meteorological variables on transmission. More broadly, I will argue that interdisciplinary approaches based on explicit causal frameworks are crucial for reliably estimating the effect of weather and accurately predicting the consequences of climate change. 
Contact: Lulla Opatowski

Tuesday, Dec 17th, 2024

12noon -1pm

Institut Pasteur / Online

Full Schedule 2024-2025

Sonja Lehtinen Evolutionary epidemiology of antibiotic resistance Tuesday, Sept 10th, 2024
12noon -1pm

Institut Pasteur / Online
Nick HengartnerIncorporating the observational process when analyzing epidemics dataTuesday, Nov 5th, 2024
12noon -1pm

Institut Pasteur / Online
Matthieu Domenech de CellesHow causal inference concepts can guide research into the effects of climate on infectious diseasesTuesday, Dec 17th, 2024

12noon -1pm

Institut Pasteur (Jules Bordet) / Online
Nathanael HozeTuesday, Jan 14th, 2024
12noon -1pm

Institut Pasteur / Online

Full Schedule 2023-2024

Amandine Veber Modelling the dynamics of genetic diversity in a spatially structured populationTuesday, Sept 5th, 2023
12noon -1pm

Institut Pasteur / Online
Juan VesgaModelling CCHF spillover in high endemic settings and the potential impact of vaccines  Tuesday, Oct 4th, 2023
12noon -1pm

Institut Pasteur / Online
Kris Parag (Imperial College London)Ineffective reproduction numbers.
What do conventional measures of infectious disease transmissibility fail to measure?
Wednesday, Dec 13th, 2023
12noon -1pm

Institut Pasteur / Online
Stefan Flashe (LSHTM)Pathogen interactions: relevant for vaccine decision making?Wednesday, Jan 17th, 2024
12noon -1pm
Institut Pasteur / Online
James Hay (Oxford Big Data Institute, UK)Using quantitative biomarkers to track infectious disease dynamicsFriday, Feb 2nd, 2024
12noon -1pm
Institut Pasteur / Online
Kevin Foster (Univ of Oxford)Competition and warfare in bacteria and the human microbiomeTuesday, March 12th
12noon -1pm
Institut Pasteur / Online
Georg Gerber (Harvard)Novel Machine Learning Methods for Dissecting the Microbiome to Improve Human HealthTuesday, April 2nd
12noon -1pm
Institut Pasteur / Online
Sebastian Duchenes (Institut Pasteur)The impact of sequence sampling times in infectious disease phylodynamicsTuesday, May 14
12noon -1pm
Institut Pasteur / Online
Luis Almeida (CNRS and Sorbonne Université)

Mathematical models for mosquito and pest population control

Tuesday, June 4
12noon -1pm
Institut Pasteur / Online

Full Schedule 2022-2023

Eugenio Valdano    Non-selective distribution of infectious disease prevention may outperform risk-based targetingWednesday, Sept 14th, 2022
12 noon -1 pm
Institut Pasteur
François MassolSome uses of network methods to understand host-microbiota interactionsOct 4th 2022
12 noon -1 pm
Institut Pasteur
Aleksandra Walczak & Thierry MoraImmune repertoires: dynamics and co-evolution with pathogensWednesday, Nov 16th 2022
12 noon -1 pm
Institut Pasteur
Florence DebarreStochastic models of early epidemics, and their applications to Covid-19Wednesday, Dec 7th 2022
12 noon -1 pm
Institut Pasteur
Samuel AlizonHow host heterogeneity impacts the way (co)infections spreadWednesday, Jan 4th 2023
12 noon -1 pm
Institut Pasteur
Niel HensOn risk perception and contact behaviour during the COVID-19 pandemicWednesday, March 8th 2023
12 noon -1 pm
Institut Pasteur
Florence BanseptEvolution in biphasic life cyclesTuesday, April 4th 2023
12 noon -1 pm
Institut Pasteur
Marga Pons SalortEmergence of enteroviruses as novel causes of diseases: opportunities to infer changes in their circulation dynamics from sero-epidemiology dataWednesday, May 17th 2023
12 noon -1 pm
Institut Pasteur
Warren TennantTuesday, June 6th 2023
12 noon -1 pm
Institut Pasteur

Schedule 2021-2022

Mircea Sofonea
Nested dynamics for the evolutionary epidemiology of multiple infections

Wednesday, Sept 8th 2021,

12 noon -1 pm
Online

Fabien CrausteMathematical and Computational Immunology: Differentiation, Heterogeneity, and Multiscale Descriptions of the CD8 T Cell Immune Response

Tuesday, Oct 5th 2021,

12 noon -1 pm
Online

Joshua Weitz Pandemic Theory and Pasteur’s Quadrant: On the Ongoing Need for Response
and Mitigation Instruments

Tuesday, Nov 9th 2021,

12 noon -1 pm
Online

Ben Cooper
Determining appropriate antibiotic treatment duration and understanding its impact on antimicrobial resistance. 

Wed, Dec 15th 2021,
12noon – 1pm
Online

Frederik GrawDeciphering infection and immune processes within tissues

Wed, Feb 16th 2022, 12noon -1pm
Online

Manlio De DomenicoCoupling human behavior with epidemic spreading: multilayer networks and the distorting lens of human mobility dataTuesday March 8th 2022
12noon -1pm
Online
Claude LoverdoBacteria in the digestive tract : Evolution in a flow; and stochastic models of population dynamics for inferring colonization probability.Tuesday April 19th 2022
12noon -1pm
Institut Pasteur / Online
Guillaume FourniéAvian influenza transmission and control across live poultry trading networks Wed June 8th 2022
12noon -1pm
Institut Pasteur / Online

Schedule 2020-2021

Oliver Ratmann
Sources of HIV infections among young & adolescent women in Africa: estimates from population-based viral phylogenetic deep sequence data

Tuesday, March 16th 2021,

12 noon -1 pm
Online

Benoit LiquetSparse Group Models for leveraging Pleiotropy effect from genome-wide association studies

Tuesday, April 13th 2021

10am-11am

Online

Andrea WilsonInvestigating and modelling the impact of vaccines and genetic selection on infectious disease transmission in farmed animals

Wednesday, May 12th

12noon-1pm

Online

Michael WhiteMathematical modelling of novel serological diagnostic tools for malaria and coronaviruses

Wednesday, June 16th

12noon-1pm

Online

Full Schedule 2019-2020

Marc BaguelinMathematical modelling to inform public health policies: shorts stories on influenza vaccination in the UK and ebola epidemics
Wednesday, Sept 25th, 2019
12 noon -1 pm
Institut Pasteur
Samuel SoubeyrandInferring epidemiological links from deep sequencing data with a statistical learning approachWednesday, Oct 16th, 2019
12 noon -1 pm
Institut Pasteur
Eric VolzHidden population structure in pathogen phylogeniesWednesday, Nov 13th, 201912 noon -1 pm
Institut Pasteur
France MentréModelling the impact of gut exposure to moxifloxacin (MXF) on the temporal changes in gut microbiota diversity in healthy volunteersTuesday, Dec 10th, 201912 noon -1 pm
Institut Pasteur
Gabriela GomezUnveiling the effects of individual variation in epidemiology, ecology and evolution

Tuesday, Jan 14th, 2020

12 noon -1 pm
Institut Pasteur

France MentréModelling the impact of gut exposure to moxifloxacin (MXF) on the temporal changes in gut microbiota diversity in healthy volunteers

Tuesday, Feb 25th, 2020

12 noon -1 pm
Institut Pasteur

Nicole MideoUnveiling the effects of individual variation in epidemiology, ecology and evolution

Wednesday, Mar 11th, 2020

12 noon -1 pm
Institut Pasteur

Full Schedule 2018-2019

Alberto d’Onofrio Behavioural Epidemiology and its limitations: A talk based on very simple models Tuesday, Sept 11th, 2018
12 noon -1 pm
Institut Pasteur
Amphitheatre Monod
Michael BlumPolygenic risk score: is there room for improvement?Wednesday, Oct 3rd, 2018
12 noon -1 pm
Institut Pasteur
 Rowland KaoModelling explorations in bovine Tuberculosis: Investigations in a unique natural laboratoryTuesday, Nov 20th, 2018
12 noon -1 pm
Institut Pasteur
 Marc Chadeau-HyamDeveloping hidden Markov Models for lung cancer risk and dynamicsTuesday, Dec 4th, 2018
12 noon -1 pm
Institut Pasteur
 Béatrice LarocheInférence de dynamiques écologiques du microbiote digestif et lien avec des modèles épidémiologiquesWednesday, Jan 9th, 2019
12 noon -1 pm
Institut Pasteur
 Anne CoriStatistical modelling for real-time outbreak response: Recent examples on Ebola and other pathogensTuesday, Feb 5th, 2019
12 noon -1 pm
Institut Pasteur
 Nicola PerraForecasting the spreading of diseases in the digital eraWednesday, March 27th, 2019
12 noon -1 pm
Institut Pasteur
Christian AlthausCauses and consequences of variation in human papillomavirus vaccination uptake in SwitzerlandTuesday, April 16th, 2019
12 noon -1 pm
Institut Pasteur
Shweta Bansal From Social Behavior to Network Structure for Wildlife Disease TransmissionTuesday, May 7th, 2019
12 noon -1 pm
Institut Pasteur
Eugenio Valdano Predicting epidemic risk from contact and mobility dataTuesday, June 4th, 2019
12 noon -1 pm
Institut Pasteur

Full Schedule 2017-2018

Benoit DurandAnalysis of the Spatial Organization of Pastures as a Contact Network, Implications for Potential Disease Spread and Biosecurity in Livestock, France, 2010

Tuesday, Sept 5th, 2017
12 noon -1 pm
Institut Pasteur
Room BIME 28-01-01A

Thibaut JombartThe R Epidemics Consortium: building the next generation of statistical tools for outbreak response using RTuesday, Oct 4th, 2017
12 noon -1 pm
Institut Pasteur
Room BIME 28-01-01A
 David Paltiel Do Less Harm: Evaluating HIV Programmatic Alternatives in Response to Cutbacks in Foreign Aid Wednesday, Nov 14th, 2017
12 noon -1 pm
Institut Pasteur
Room auditorium François Jacob
 Thibaud Porphyre  Climbing the ladder to preparedness: modelling the spread of swine fevers in Great Britain Wednesday, Dec 13th, 2017
12 noon -1 pm
Institut Pasteur
Room auditorium François Jacob
 François Blanquart  The epidemiology and evolution of HIV-1 virulence Wednesday, Jan 10th, 2018
12 noon -1 pm
Institut Pasteur
Room TBA

Tini Garske

 The Vaccine Impact Modelling Consortium: Estimating the mortality and morbidity averted through childhood vaccination programmes in low and middle income countries Wednesday, Feb 7th, 2018
12 noon -1 pm
Institut Pasteur
Room TBA

 Cécile Viboud

Spatial dynamics and forecasting of infectious diseases: application to influenza and Ebola  Tuesday, March 13th, 2018
12 noon -1 pm
Institut Pasteur
Room Jean-Paul Aubert

 Troy Day

Can we use mathematical modeling to design evolution-proof drugs?  Tuesday, April 17th, 2018
12 noon -1 pm
Institut Pasteur
Room Jean-Paul Aubert
 Matt Ferrari Better with age: insights on measles persistence and control

 Wednesday May 2nd 2018
12 noon -1pm
Institut Pasteur

Marc LipsitchWhy haven’t antibiotic-resistant bacteria (pneumococci, at least) taken over the world?Tuesday, June 19th 2018
12 noon -1pm
Institut Pasteur
Room Jean-Paul Aubert

Full Schedule 2016-2017

Raphaëlle METRAS Studying drivers for arboviral emergence: the case of Rift Valley fever in MayotteAbstractWednesday, Sept 7th, 2016
12 noon -1 pm
Room BIME 28-01-01A
Rebecca GRAISA heat-stable rotavirus vaccine: a Phase III trial in NigerAbstractFriday, Oct 14th, 2016
12 noon -1 pm
Room BIME 28-01-01A
Christophe FRASERTracking and tackling the HIV-1 pandemic: models, evolution, genomics AbstractWednesday, Nov 9th, 2016
12 noon -1 pm
Room Retrovirus
Niel HENSUsing frailty models to quantify heterogeneity in acquisition of infectious diseases based on multivariate serological dataAbstractTuesday, Dec 6th, 2016
12 noon -1 pm
Room Jean Paul  Aubert
Kevin JEANModelling Yellow Fever burden in Africa: insights for short- and long-term control strategies. AbstractWednesday, Jan 4th, 2017
12 noon -1 pm
Room BIME 28-01-01A
Michele TIZZONI Fast and accurate dynamic estimation of field effectiveness of meningococcal vaccinesThursday, Feb 2nd, 2017
12 noon -1 pm
Room Jean Paul  Aubert
Anne GOELZERQuantitative prediction of genome-wide resource allocation in bacteriaTuesday, March 7th, 2017
12 noon -1 pm
Room Jean Paul  Aubert
Viet Chi TranModèles mathématiques pour des épidémies se propageant sur des graphes aléatoiresWednesday, April 19th, 2017
12 noon -1 pm
Room Retrovirus
Karoline Faust Modeling the dynamics of a synthetic gut community Wednesday, May 3rd, 2017
12 noon -1 pm
Room Retrovirus
Romulus Breban Diffusion within Populations: From Infectious Diseases and Market Sales to Fashion First NamesThursday, June 8th, 2017
12 noon -1 pm
Room Jean Paul  Aubert

Full Schedule 2015-2016

Henrik SALJEUse of mathematical modelling to reconstruct 60 years of chikungunya epidemiology in the PhilippinesAbstractWed, Sep 9th, 2015
12 noon -1 pm
Room Jean-Paul Aubert
Anton CAMACHO The impact of dynamical modelling on public-health decisions made during the 2013-2015 Ebola outbreakAbstractTuesday, Oct 6th, 2015
  12 noon -1 pm
Room BIME 28-01-01A
Marc LAVIELLEModeling and simulation of complex pharmacometric models: methods and toolsAbstractTue, Nov 3rd, 2015
  12 noon -1 pm
Room BIME 28-01-01A
David CLAESSENEco-evolutionary dynamics in spatially complex systems: from agro-ecology to the global oceanAbstractTue, Dec 8th, 2015
12 noon -1 pm
Room Jean-Paul Aubert
Jean-Pierre NADALModeling the contagion dynamics of the 2005 French riotsAbstractTuesday, Jan 5th, 2016
  12 noon -1 pm
Room BIME 28-01-01A
Mathieu ANDRAUDInfectious diseases in pigs: from parameter estimation to dynamic modelsAbstractTue, Feb 9th, 2016
  12 noon -1 pm
Room BIME 28-01-01A
Marcel SALATHéDigital Epidemiology: Opportunities & Challenges of an Evolving FieldAbstractWed, March 16th, 2016
  12 noon -1 pm
Room BIME 28-01-01A
Daniela DE ANGELISPrediction of antibiotic resistance in Staphylcoccus aureusAbstractTue, April 5th, 2016
  12 noon -1 pm
Room Jean-Paul Aubert
Philippe LEMEYPhylodynamic inference in viral outbreaks: power and limitations.AbstractTue, May 3rd, 2016
  12 noon -1 pm
Room BIME 28-01-01A
Hans BOGAARDSSecond-guessing the clustering of multiple HPV types: prospects of type replacement following mass immunizationAbstractTue, June 14th, 2016
  12 noon -1 pm
Room BIME 28-01-01A

Full Schedule 2014-2015

Yamir MORENODynamics of Interacting DiseasesAbstractTue, Sep 9th, 2014
12 noon -1 pm
Room Jean-Paul Aubert
Chiara POLLETOModelling disease spatial spread and real time assessment of emerging pathogen eventsAbstractWed, Oct 8th, 2014
  12 noon -1 pm
Room BIME 28-01-01A
Gilles WAINRIBIntegrative network inference of gene expression data and applications to inflammatory bowel diseaseAbstractTue, Nov 4th, 2014
  12 noon -1 pm
Room Jean-Paul Aubert
Christian ROBERTABC methods for Bayesian model choiceAbstractTue, Dec 2nd, 2014
12 noon -1 pm
Room DUCLAUX RDC HAUT
Guillaume ACHAZThe strange case of the Standard Neutral Model of molecular evolution: when, what and whyAbstractTue, Jan 13th, 2015
 12 noon -1 pm
Room DUCLAUX RDC HAUT
Nicolas BACAEREpidemic models and seasonalityAbstractTue, Feb 10th, 2015
12 noon -1 pm
Room BIME 28-01-01A
Benoit PERTHAMEKinetic models of chemotaxis and traveling pulsesAbtractTue, Mar 10th, 2015
  12 noon -1 pm
Room DUCLAUX RDC HAUT
Samuel ALIZONWhy does HIV harm its host? Clinical and epidemiological applications of virus phylogeniesAbstractTue, Apr 14th, 2015
  12 noon -1 pm
Room BIME 28-01-01A
Alan PERELSONMathematical modeling and the potential cure of HIVAbstractWed, May 20th, 2015
  12 noon -1 pm
Room Retrovirus
Ron BROOKMEYERTracking the AIDS Epidemic: Estimating HIV IncidenceAbtractTue, June 2nd, 2015 
12 noon -1 pm
Pitié Salpétrière hospital,
Ecologie Cellulaire bldg.

Full Schedule 2013-2014

Alun LLOYDModeling novel strategies for controlling mosquito-borne diseasesAbstractTue, Sep 24th, 2013 
12 noon -1 pm
Room Jean-Paul Aubert
Joseph DUREAU The Public Library of Models: an open source project towards social modelingAbstractTue, Oct 8th, 2013 
12 noon -1 pm 

Room Jules Bordet
Julia GOGCapturing the spread and evolution of influenza AAbstractTue, Nov 5th, 2013 
12 noon -1 pm
Room Jean-Paul Aubert
Véronique THOMAS-VASLINModélisation de la dynamique lymphocytaire T AbstractTue, Dec 10th, 2013 
12 noon -1 pm 

Room Jean-Paul Aubert
Bernard
 CAZELLESWavelet analysis as a tool for considering non-stationarity in EpidemiologyAbstractTue, Jan 7th, 2014 
12 noon -1 pm 

Room Jean-Paul Aubert
Jeremie GUEDJModeling hepatitis C viral kinetic in the era of direct acting antiviral agents: review and perspectivesAbstractTue, Feb 11th, 2014
12 noon -1 pm 

Room Jean-Paul Aubert
Peter WHITETackling TB in the Age of Austerity: ensuring we use novel tools and approaches cost-effectively AbstractTue, Mar 4th, 2014
12:30 noon -1:30 pm

Room Jean-Paul Aubert  
Aurélien LATOUCHERegression modeling of the cumulative incidence function with missing causes of failureAbstractTue, Apr 1st, 2014
12 noon -1 pm

Room Jean-Paul Aubert 
Aaron KINGHow to tell if the honeymoon is over: testing hypotheses about pertussis and its resurgenceAbstractTue, May 6th, 2014
12 noon -1 pm 

Room Jean-Paul Aubert 
Carlo Giovanni CAMARDAModelling Social Contact Data: a smoothing constrained approachAbstractTue, Jun 10h, 2014
12 noon -1 pm 

Room Jean-Paul Aubert 

Fundings