Timeline
Fabrice Agou
Head of Facility
06 Jan 2024
publication
PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial.
Read more27 Oct 2023
event
ATC-DDS Seminar – “Epigenetic regulation: at the apex of Innate Immune Memory” – Pr. Musa M. Mhlanga (Radboud University, Netherlands)
Read more13 Jul 2023
event
2nd Drug Discovery & Screening Symposium – “From bench to drug discovery” – an ATC-DDS initiative
Read more21 Apr 2023
publication
Enhanced neutralization escape to therapeutic monoclonal antibodies by SARS-CoV-2 omicron sub-lineages.
Read more22 Mar 2023
30 Nov 2022
publication
High-Content RNAi Phenotypic Screening Unveils the Involvement of Human Ubiquitin-Related Enzymes in Late Cytokinesis
Read more29 Aug 2022
04 Jul 2022
publication
Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
Read more17 Jun 2022
news
New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2
Read more01 May 2022
publication
A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors.
Read more27 Sep 2021
publication
Interrogating RNA and protein spatial subcellular distribution in smFISH data with DypFISH
Read more21 Sep 2021
publication
Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential.
Read more04 Nov 2019
publication
A sensitive fluorescence-based assay to monitor enzymatic activity of the essential integral membrane protein Apolipoprotein N-acyltransferase (Lnt).
Read more25 Sep 2019
publication
Two NEMO-like Ubiquitin-Binding Domains in CEP55 Differently Regulate Cytokinesis.
Read more29 Jan 2019
event
Virology Department Seminar : « Molecular mechanisms of enterovirus infection and search for anti-virals » with Varpu MARJOMÄKI
Read more13 Dec 2017
13 Dec 2017
13 Dec 2017
27 Feb 2017
publication
Lack of interaction between NEMO and SHARPIN impairs linear ubiquitination and NF-κB activation and leads to incontinentia pigmenti.
Read more02 Sep 2016
publication
Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti
Read more27 Oct 2015
05 Jun 2015
01 Feb 2015
publication
Use of fluorescence spectroscopy for quantitative investigations of ubiquitin interactions with the ubiquitin-binding domains of NEMO
Read more01 Jan 2015
20 Jan 2014
publication
TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structures.
Read more23 Jul 2011
publication
Direct inhibition of NF-κB activation by peptide targeting the NOA ubiquitin binding domain of NEMO
Read more23 Oct 2009
publication
DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding
Read more25 Nov 2008
30 Jan 2008
publication
Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation
Read more01 Sep 2007
publication
Inhibition of NF-kappaB activation with designed ankyrin-repeat proteins targeting the ubiquitin-binding/oligomerization domain of NEMO
Read more10 Apr 2007
publication
NEMO oligomerization in the dynamic assembly of the IkappaB kinase core complex
Read more23 Apr 2004
publication
The trimerization domain of NEMO is composed of the interacting C-terminal CC2 and LZ coiled-coil subdomains
Read more01 Jan 2004