Timeline

Natalia Pietrosemoli

Research Engineer

08 Oct 2024

tool

EXOTICS

30 Sep 2024

publication

Leptospira interrogans biofilm transcriptome highlights adaption to starvation and general stress while maintaining virulence.

01 Jun 2024

publication

A regionally based precision medicine implementation initiative in North Africa:The PerMediNA consortium.

30 Nov 2023

publication

Transcriptome profiling of human col\onic cells exposed to the gut pathobiont Streptococcus gallolyticus subsp. gallolyticus.

12 Sep 2023

publication

Hemostasis defects underlying the hemorrhagic syndrome caused by Mammarenaviruses in a cynomolgus macaque model.

17 Jul 2023

course

Bioinformatics program for PhD students 2023 2024

11 Mar 2023

publication

Rapid protection induced by a single-shot Lassa vaccine in male cynomolgus monkeys.

01 Jan 2023

publication

A MOPEVAC multivalent vaccine induces sterile protection against New World arenaviruses in non-human primates.

01 Jan 2023

publication

Phenotypes controlled by the Brucella abortus two component system BvrR/BvrS are differentially impacted by BvrR phosphorylation.

01 Jan 2023

publication

Multi-Modal SARS-CoV-2 Proteins Interactomics Unveil Spatial Patterns of Invasion Featuring 151 Contacts with Human Proteins Essential for Infection

01 Dec 2022

publication

Pathogenesis of recent Lassa virus isolates from lineages II and VII in cynomolgus monkeys.

23 Sep 2022

course

PHINDaccess – Comparative Genomics

11 Jul 2022

course

Bioinformatics program for PhD students 2022-2023

31 May 2022

course

PHINDaccess – Functional OMICs

21 Mar 2022

publication

Infection of Human Endothelial Cells with Lassa Virus Induces Early but Transient Activation and Low Type I IFN Response Compared to the Closely-Related Nonpathogenic Mopeia Virus.

22 Oct 2021

publication

Dichotomous metabolic networks govern human ILC2 proliferation and function.

16 Jun 2021

event

DCB Seminar Series “The Gene Ontology: what you need to know”

04 Jan 2021

publication

Systemic viral spreading and defective host responses are associated with fatal Lassa fever in macaques.

24 Sep 2020

course

Bioinformatics program for PhD students 2020-2021

22 Sep 2020

publication

Influenza A virus co-opts ERI1 exonuclease bound to histone mRNA to promote viral transcription.

30 Oct 2019

event

Extendable benchmarks and interactive exploratory analysis of single-cell RNA-seq data

02 Oct 2019

publication

Vaccines inducing immunity to Lassa virus glycoprotein and nucleoprotein protect macaques after a single shot.

28 Sep 2019

project

PHINDaccess

19 Sep 2019

event

CANCELLED : DBC Seminar — Alfonso Valencia: Computational Biology in the Crossroad of Big Data, Artificial Intelligence and High Performance Computing

27 Jun 2019

software

g-RITA

12 Jun 2019

course

High Throughput Sequencing Data Analysis on Genomics, Metagenomics and Transcriptomics

17 May 2019

event

[C3BI Seminar & INCEPTION] Chris Adami- Evolution of information in HIV-1 protease

26 Apr 2019

event

A population genetic interpretation of complex trait architecture in humans

21 Mar 2019

publication

Non-Pathogenic Mopeia Virus Induces More Robust Activation of Plasmacytoid Dendritic Cells than Lassa Virus

22 Feb 2019

event

[C3BI Seminar] – Nevan Krogan: Using Systems Approaches to Understand the Mechanism of Disease

04 Feb 2019

event

[C3BI Seminar]- Amine Ghozlane: The human gut resistome

29 Jan 2019

event

[C3BI Seminar]- Zamin Iqbal: Nucleotide-level analysis of genetic variation in the bacterial pan-genome

16 Jan 2019

event

[C3BI Seminar]- Yves Moreau: Bayesian matrix factorization for drug discovery and precision medicine

10 Jan 2019

publication

Immune parameters and outcomes during Ebola virus disease

01 Nov 2018

publication

Lassa virus activates myeloid dendritic cells but suppresses their ability to stimulate T cells.

27 Sep 2018

tool

Sherpa

27 Sep 2018

tool

coGSEA

19 Jul 2018

course

Morning session – Introduction to NGS data analysis

18 Jun 2018

publication

Proteomics reveals scope of mycolactone-mediated Sec61 blockade and distinctive stress signature

28 Mar 2018

team

Expertise group : SysBio – System Bioinformatics

01 Jan 2018

publication

Optimized Protein-Protein Interaction Network Usage with Context Filtering

22 Dec 2017

publication

Comparison of multiple transcriptomes exposes unified and divergent features of quiescent and activated skeletal muscle stem cells.

05 Jul 2017

publication

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

05 Jul 2017

publication

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

11 Nov 2016

event

Ecole thématique – Bioinformatics of protein-protein interactions for wet lab scientists

20 Apr 2016

course

Training: analysis of the transcriptome by RNAseq

26 Jun 2015

team

Bioinformatics and Biostatistics HUB

09 Apr 2015

publication

A 12-gene signature to distinguish colon cancer patients with better clinical outcome following treatment with 5-fluorouracil or FOLFIRI

24 Dec 2013

publication

Structural basis for the broad specificity of a new family of amino-acid racemases

12 Sep 2013

publication

Protein intrinsic disorder in plants

18 Jul 2013

publication

Structural disorder provides increased adaptability for vesicle trafficking pathways

07 Feb 2013

publication

Genome-wide analysis of protein disorder in Arabidopsis thaliana: implications for plant environmental adaptation

07 Nov 2012

publication

Computational prediction of important regions in protein sequences

21 Mar 2009

publication

An automatic method for colon segmentation in CT colonography

02 Aug 2007

publication

A little guide for advanced search:

EXOTICS

Leptospira interrogans biofilm transcriptome highlights adaption to starvation and general stress while maintaining virulence.

A regionally based precision medicine implementation initiative in North Africa:The PerMediNA consortium.

Transcriptome profiling of human col\onic cells exposed to the gut pathobiont Streptococcus gallolyticus subsp. gallolyticus.

Hemostasis defects underlying the hemorrhagic syndrome caused by Mammarenaviruses in a cynomolgus macaque model.

Bioinformatics program for PhD students 2023 2024

Rapid protection induced by a single-shot Lassa vaccine in male cynomolgus monkeys.

A MOPEVAC multivalent vaccine induces sterile protection against New World arenaviruses in non-human primates.

Phenotypes controlled by the Brucella abortus two component system BvrR/BvrS are differentially impacted by BvrR phosphorylation.

Multi-Modal SARS-CoV-2 Proteins Interactomics Unveil Spatial Patterns of Invasion Featuring 151 Contacts with Human Proteins Essential for Infection

Pathogenesis of recent Lassa virus isolates from lineages II and VII in cynomolgus monkeys.

PHINDaccess – Comparative Genomics

Bioinformatics program for PhD students 2022-2023

PHINDaccess – Functional OMICs

Infection of Human Endothelial Cells with Lassa Virus Induces Early but Transient Activation and Low Type I IFN Response Compared to the Closely-Related Nonpathogenic Mopeia Virus.

Dichotomous metabolic networks govern human ILC2 proliferation and function.

DCB Seminar Series “The Gene Ontology: what you need to know”

Systemic viral spreading and defective host responses are associated with fatal Lassa fever in macaques.

Bioinformatics program for PhD students 2020-2021

Influenza A virus co-opts ERI1 exonuclease bound to histone mRNA to promote viral transcription.

Extendable benchmarks and interactive exploratory analysis of single-cell RNA-seq data

Vaccines inducing immunity to Lassa virus glycoprotein and nucleoprotein protect macaques after a single shot.

PHINDaccess

CANCELLED : DBC Seminar — Alfonso Valencia: Computational Biology in the Crossroad of Big Data, Artificial Intelligence and High Performance Computing

g-RITA

High Throughput Sequencing Data Analysis on Genomics, Metagenomics and Transcriptomics

[C3BI Seminar & INCEPTION] Chris Adami- Evolution of information in HIV-1 protease

A population genetic interpretation of complex trait architecture in humans

Non-Pathogenic Mopeia Virus Induces More Robust Activation of Plasmacytoid Dendritic Cells than Lassa Virus

[C3BI Seminar] – Nevan Krogan: Using Systems Approaches to Understand the Mechanism of Disease

[C3BI Seminar]- Amine Ghozlane: The human gut resistome

[C3BI Seminar]- Zamin Iqbal: Nucleotide-level analysis of genetic variation in the bacterial pan-genome

[C3BI Seminar]- Yves Moreau: Bayesian matrix factorization for drug discovery and precision medicine

Immune parameters and outcomes during Ebola virus disease

Lassa virus activates myeloid dendritic cells but suppresses their ability to stimulate T cells.

Sherpa

coGSEA

Morning session – Introduction to NGS data analysis

Proteomics reveals scope of mycolactone-mediated Sec61 blockade and distinctive stress signature

Expertise group : SysBio – System Bioinformatics

Optimized Protein-Protein Interaction Network Usage with Context Filtering

Comparison of multiple transcriptomes exposes unified and divergent features of quiescent and activated skeletal muscle stem cells.

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

Ecole thématique – Bioinformatics of protein­-protein interactions for wet lab scientists

Training: analysis of the transcriptome by RNAseq

Bioinformatics and Biostatistics HUB

A 12-gene signature to distinguish colon cancer patients with better clinical outcome following treatment with 5-fluorouracil or FOLFIRI

Structural basis for the broad specificity of a new family of amino-acid racemases

Protein intrinsic disorder in plants

Structural disorder provides increased adaptability for vesicle trafficking pathways

Genome-wide analysis of protein disorder in Arabidopsis thaliana: implications for plant environmental adaptation

Computational prediction of important regions in protein sequences

An automatic method for colon segmentation in CT colonography

Dehydration propensity of order-disorder intermediate regions in soluble proteins

Ecole thématique – Bioinformatics of protein-protein interactions for wet lab scientists