Timeline
Michaela Muller-Trutwin
Head of Structure
23 Feb 2024
event
Work in progress (WIP) – ANRS MIE AC41 “Host-HIV interactions, basic and translational research”
Read more23 Feb 2024
news
Work in progress (WIP) – AC41 “Host-HIV interactions, basic and translational research” – May 2nd – Institut Pasteur
Read more11 Jan 2024
publication
Early antiretroviral therapy favors post-treatment SIV control associated with the expansion of enhanced memory CD8+ T-cells.
Read more04 Dec 2023
02 Nov 2023
publication
SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells.
Read more07 Aug 2023
news
ANRS MIE AC41 International symposium on Targeting the HIV reservoir – 21st november at Institut Pasteur
Read more17 May 2023
02 Sep 2022
news
ANRS-MIE AC41 International Symposium on HIV reservoirs on Nov 14 and 15 at Institut Pasteur, Paris
Read more07 Jul 2022
publication
NK cell spatial dynamics and IgA responses in gut-associated lymphoid tissues during SIV infections.
Read more18 Apr 2022
publication
CXCR3 Expression Pattern on CD4+ T Cells and IP-10 Levels with Regard to the HIV-1 Reservoir in the Gut-Associated Lymphatic Tissue.
Read more05 Apr 2022
publication
Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control.
Read more25 Feb 2022
04 Feb 2022
30 Nov 2021
22 Oct 2021
27 Aug 2021
07 Jun 2021
news
Immunothérapie permettant à des cellules du système immunitaire inné de contribuer au contrôle du VIH après un arrêt du traitement antiviral
Read more17 May 2021
publication
IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques.
Read more05 May 2021
publication
Ultrasensitive Detection of p24 in Plasma Samples from People with Primary and Chronic HIV-1 Infection.
Read more01 May 2021
publication
HIV DNA reservoir and elevated PD-1 expression of CD4 T-cell subsets particularly persist in the terminal ileum of HIV-positive patients despite cART.
Read more23 Apr 2021
publication
Role of NKG2a/c+CD8+ T cells in pathogenic versus non-pathogenic SIV infections.
Read more24 Feb 2021
publication
SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity.
Read more01 Feb 2021
publication
Analysis and annotation of DNA methylation in two nonhuman primate species using the Infinium Human Methylation 450K and EPIC BeadChips.
Read more01 Jan 2021
publication
CD32+CD4+ T Cells Sharing B Cell Properties Increase With Simian Immunodeficiency Virus Replication in Lymphoid Tissues.
Read more09 Dec 2020
publication
DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4 + T cells in response to SIV infections.
Read more22 Sep 2020
publication
Optimal Maturation of the SIV-Specific CD8+ T Cell Response after Primary Infection Is Associated with Natural Control of SIV: ANRS SIC Study.
Read more01 Sep 2020
publication
Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation.
Read more01 Jul 2020
publication
Antiapoptotic Clone 11-Derived Peptides Induce In Vitro Death of CD4+ T Cells Susceptible to HIV-1 Infection.
Read more01 Jul 2020
publication
Extremely low viral reservoir in treated chronically HIV-1-infected individuals.
Read more18 Jun 2020
publication
TLR7 dosage polymorphism shapes interferogenesis and HIV-1 acute viremia in women.
Read more01 Jan 2020
publication
Non-human Primate Determinants of Natural Killer Cells in Tissues at Steady-State and During Simian Immunodeficiency Virus Infection.
Read more19 Sep 2019
03 Sep 2019
01 Aug 2019
01 Jul 2019
publication
Metabolic plasticity of HIV-specific CD8+ T cells is associated with enhanced antiviral potential and natural control of HIV-1 infection.
Read more01 Jun 2019
01 May 2019
01 Apr 2019
26 Mar 2019
05 Mar 2019
publication
Cellular Metabolism Is a Major Determinant of HIV-1 Reservoir Seeding in CD4+ T Cells and Offers an Opportunity to Tackle Infection.
Read more01 Nov 2018
publication
Publisher Correction: Ancient hybridization and strong adaptation to viruses across African vervet monkey populations.
Read more01 Oct 2018
publication
Effect of schistosomiasis on the outcome of patients infected with HIV-1 starting antiretroviral therapy in rural Tanzania.
Read more20 Sep 2018
27 Aug 2018
03 Jul 2018
news
Satellite Symposium at the International HIV Conference in Amsterdam: ” How Far are We from HIV Remission?
Read more01 Jul 2018
publication
Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC+ CD4+ cell levels: a surrogate marker candidate of HIV-induced intestinal damage.
Read more01 Jun 2018
10 Apr 2018
publication
Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity.
Read more09 Apr 2018
01 Apr 2018
01 Jan 2018
publication
Lymph Node Cellular and Viral Dynamics in Natural Hosts and Impact for HIV Cure Strategies.
Read more01 Dec 2017
publication
High proportion of PD-1-expressing CD4+ T cells in adipose tissue constitutes an immunomodulatory microenvironment that may support HIV persistence.
Read more01 Dec 2017
publication
p21 Restricts HIV-1 in Monocyte-Derived Dendritic Cells through the Reduction of Deoxynucleoside Triphosphate Biosynthesis and Regulation of SAMHD1 Antiviral Activity.
Read more01 Dec 2017
publication
Ancient hybridization and strong adaptation to viruses across African vervet monkey populations.
Read more17 Nov 2017
02 Nov 2017
01 Nov 2017
publication
Natural killer cells migrate into and control simian immunodeficiency virus replication in lymph node follicles in African green monkeys.
Read more17 Oct 2017
news
Natural killer cells migrate into and control simian immunodeficiency virus replication in lymph node follicles in African green monkeys
Read more01 Jul 2017
publication
NKG2C+ memory-like NK cells contribute to the control of HIV viremia during primary infection: Optiprim-ANRS 147.
Read more15 Mar 2017
publication
Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents.
Read more15 Feb 2017
publication
CXCR6-Mediated Simian Immunodeficiency Virus SIVagmSab Entry into Sabaeus African Green Monkey Lymphocytes Implicates Widespread Use of Non-CCR5 Pathways in Natural Host Infections.
Read more09 Jan 2017
01 Jan 2017
publication
Impact of early cART on HIV blood and semen compartments at the time of primary infection.
Read more01 Jan 2017
publication
A Mature NK Profile at the Time of HIV Primary Infection Is Associated with an Early Response to cART.
Read more01 Dec 2016
01 Aug 2016
publication
Innate immune cell responses in non pathogenic versus pathogenic SIV infections.
Read more01 Aug 2016
publication
Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset.
Read more30 Apr 2016
30 Apr 2016
03 Mar 2016
01 Mar 2016
publication
Immune activation in HIV infection: what can the natural hosts of simian immunodeficiency virus teach us?
Read more12 Feb 2016
12 Jan 2016
publication
Endogenous TRIM5α Function Is Regulated by SUMOylation and Nuclear Sequestration for Efficient Innate Sensing in Dendritic Cells.
Read more01 Jan 2016
publication
Dendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles.
Read more01 Dec 2015
08 Sep 2015
08 Sep 2015
04 Sep 2015
04 Sep 2015
04 Sep 2015
03 Sep 2015
01 Sep 2015
publication
Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection.
Read more01 Jul 2015
publication
Second European Round Table on the Future Management of HIV: 10-11 October 2014, Barcelona, Spain.
Read more01 Jul 2015
publication
Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection.
Read more11 May 2015
01 Apr 2015
publication
Cryptococcal Antigenemia in Immunocompromised Human Immunodeficiency Virus Patients in Rural Tanzania: A Preventable Cause of Early Mortality.
Read more01 Apr 2015
01 Jan 2015
publication
Modulation of type I interferon-associated viral sensing during acute simian immunodeficiency virus infection in African green monkeys.
Read more11 Oct 2014
01 Sep 2014
publication
Total ankle replacement in patients with haemophilia and virus infections–a safe alternative to ankle arthrodesis?
Read more01 Jul 2014
publication
Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection.
Read more01 Jun 2014
01 Jan 2014
publication
Immune responses during spontaneous control of HIV and AIDS: what is the hope for a cure?
Read more01 Sep 2013
publication
Patients’ satisfaction with sexual and reproductive health services delivered in HIV clinics across European regions.
Read more01 Jul 2013
13 Sep 2012
publication
Pivotal role of M-DC8+ monocytes from viremic HIV-infected patients in TNF overproduction in response to microbial products.
Read more01 Sep 2012
publication
Effect of alendronate on HIV-associated osteoporosis: a randomized, double-blind, placebo-controlled, 96-week trial (ANRS 120).
Read more22 Jun 2012
publication
Expression sequence tag library derived from peripheral blood mononuclear cells of the chlorocebus sabaeus.
Read more19 Jun 2012
publication
Innate immunity in the control of HIV/AIDS: recent advances and open questions.
Read more14 Jan 2012
publication
Level of double negative T cells, which produce TGF-β and IL-10, predicts CD8 T-cell activation in primary HIV-1 infection.
Read more01 Jan 2012
01 Jan 2012
publication
Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection.
Read more01 Jan 2012
publication
The biased nucleotide composition of HIV-1 triggers type I interferon response and correlates with subtype D increased pathogenicity.
Read more01 Sep 2011
publication
Greater diversity of HIV DNA variants in the rectum compared to variants in the blood in patients without HAART.
Read more01 Aug 2011
publication
Sexual protection behavior in HIV-positive gay men: testing a modified information-motivation-behavioral skills model.
Read more01 Aug 2010
publication
Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques.
Read more01 May 2010
15 Jan 2010
publication
AIDS progression is associated with the emergence of IL-17-producing cells early after simian immunodeficiency virus infection.
Read more15 Dec 2009
publication
[Burden of disease and level of patient’s medical care in substitution treatment for opiates].
Read more01 Dec 2009
publication
Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response.
Read more01 Aug 2009
publication
Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts.
Read more01 Mar 2009
publication
Gag p27-specific B- and T-cell responses in Simian immunodeficiency virus SIVagm-infected African green monkeys.
Read more01 Jan 2009
publication
African non human primates infected by SIV – why don’t they get sick? Lessons from studies on the early phase of non-pathogenic SIV infection.
Read more01 Jun 2008
publication
Plasmacytoid dendritic cell dynamics and alpha interferon production during Simian immunodeficiency virus infection with a nonpathogenic outcome.
Read more01 Jun 2008
publication
Effect of SIVmac infection on plasmacytoid and CD1c+ myeloid dendritic cells in cynomolgus macaques.
Read more01 Feb 2008
publication
Early divergence in lymphoid tissue apoptosis between pathogenic and nonpathogenic simian immunodeficiency virus infections of nonhuman primates.
Read more01 Dec 2007
publication
Nef-mediated enhancement of virion infectivity and stimulation of viral replication are fundamental properties of primate lentiviruses.
Read more31 Oct 2007
01 Oct 2007
publication
Long oligonucleotide microarrays for African green monkey gene expression profile analysis.
Read more26 Jun 2006
publication
Distinct expression profiles of TGF-beta1 signaling mediators in pathogenic SIVmac and non-pathogenic SIVagm infections.
Read more16 Jun 2006
publication
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.
Read more01 May 2006
publication
Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hosts.
Read more20 Jan 2006
publication
Phenotype and function of myeloid dendritic cells derived from African green monkey blood monocytes.
Read more01 Oct 2005
01 Aug 2005
01 May 2005
publication
Impact of viral factors on very early in vivo replication profiles in simian immunodeficiency virus SIVagm-infected African green monkeys.
Read more06 Apr 2005
publication
First Dominique Dormont International Conference on “Host-pathogen interactions in chronic infections – viral and host determinants of HCV, HCMV, and HIV infections”.
Read more01 Apr 2005
publication
Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS.
Read more01 Jan 2005
publication
Simian immunodeficiency virus infection in wild-caught chimpanzees from cameroon.
Read more02 Jul 2004
publication
Phylogenetic characteristics of three new HIV-1 N strains and implications for the origin of group N.
Read more01 Jul 2004
publication
Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors.
Read more01 Apr 2004
01 Apr 2004
publication
Viral load in tissues during the early and chronic phase of non-pathogenic SIVagm infection.
Read more01 Jan 2004
publication
DC-SIGN from African green monkeys is expressed in lymph nodes and mediates infection in trans of simian immunodeficiency virus SIVagm.
Read more05 Dec 2003
publication
High levels of SIVmnd-1 replication in chronically infected Mandrillus sphinx.
Read more01 Sep 2003
01 Jul 2003
publication
Broad spectrum of coreceptor usage and rapid disease progression in HIV-1-infected individuals from Central African Republic.
Read more01 Oct 2002
publication
High levels of viral replication contrast with only transient changes in CD4(+) and CD8(+) cell numbers during the early phase of experimental infection with simian immunodeficiency virus SIVmnd-1 in Mandrillus sphinx.
Read more01 Jul 2002
publication
Basic research: what is it good for AIDS epidemiology and control?. An e-debate.
Read more01 May 2002
01 Sep 2001
publication
Frequent substitution polymorphisms in African green monkey CCR5 cluster at critical sites for infections by simian immunodeficiency virus SIVagm, implying ancient virus-host coevolution.
Read more01 Aug 2001
01 Jul 2001
publication
Synthetic peptide strategy for the detection of and discrimination among highly divergent primate lentiviruses.
Read more10 Nov 2000
01 Aug 2000
publication
SIVcpz from a naturally infected Cameroonian chimpanzee: biological and genetic comparison with HIV-1 N.
Read more01 Aug 2000
publication
High levels of viral replication during primary simian immunodeficiency virus SIVagm infection are rapidly and strongly controlled in African green monkeys.
Read more01 Jan 2000
publication
env sequences of simian immunodeficiency viruses from chimpanzees in Cameroon are strongly related to those of human immunodeficiency virus group N from the same geographic area.
Read more13 Nov 1999
publication
Towards improvements in molecular tools for diagnosis and management of HIV infections.
Read more01 Jul 1999
publication
Mutations in CCR5-coding sequences are not associated with SIV carrier status in African nonhuman primates.
Read more01 Jun 1999
15 Apr 1999
01 Nov 1998
01 Sep 1998
publication
Identification of a new human immunodeficiency virus type 1 distinct from group M and group O.
Read more01 Jul 1998
publication
Genetically related human immunodeficiency virus type 1 in three adults of a family with no identified risk factor for intrafamilial transmission.
Read more10 Jun 1998
publication
Phylogenetic analysis of SIV and STLV type I in mandrills (Mandrillus sphinx): indications that intracolony transmissions are predominantly the result of male-to-male aggressive contacts.
Read more01 Jun 1997
publication
Relation between phylogeny of African green monkey CD4 genes and their respective simian immunodeficiency virus genes.
Read more01 Sep 1996
publication
The evolutionary rate of nonpathogenic simian immunodeficiency virus (SIVagm) is in agreement with a rapid and continuous replication in vivo.
Read more01 May 1996
15 Jun 1994
publication
Mosaic genome structure of simian immunodeficiency virus from west African green monkeys.
Read more01 Jan 1994
publication
Seroepidemiologic, molecular, and phylogenetic analyses of simian T-cell leukemia viruses (STLV-I) from various naturally infected monkey species from central and western Africa.
Read more01 Mar 1993
publication