Timeline

Olivera Francetic
Group Leader
08 Dec 2023
publication

Membrane platform protein PulF of the Klebsiella type II secretion system forms a trimeric ion channel essential for endopilus assembly and protein secretion.

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02 May 2023
publication

The periplasmic coiled coil formed by the assembly platform proteins PulL and PulM is critical for function of the Klebsiella type II secretion system.

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13 Apr 2023
project

Electrogenetic control of bacterial metabolism, communication, and biofilm formation

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13 Apr 2023
project

Bacterial nanowires

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27 Mar 2023
publication

Bacterial Type II Secretion System and Its Mitochondrial Counterpart.

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02 Feb 2023
publication

Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system.

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01 Feb 2023
news

Bacterial pathogenicity: improving understanding of an essential process – molecule secretion

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01 Oct 2021
publication

1 H, 15 N and 13 C resonance assignments of the C-terminal domain of PulL, a component of the Klebsiella oxytoca type II secretion system

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11 Sep 2021
publication

Computational and biochemical analysis of type IV pilus dynamics and stability.

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19 Aug 2021
publication

1H, 15 N and 13C resonance assignments of the C-terminal domain of PulL, a component of the Klebsiella oxytoca type II secretion system.

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19 May 2021
publication

Analysis of diverse eukaryotes suggests the existence of an ancestral mitochondrial apparatus derived from the bacterial type II secretion system.

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29 Nov 2019
publication

Structure and function of minor pilins of type IV pili.

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31 Jul 2019
project

Biogenesis of extracytoplasmic proteins in Gram-negative bacteria

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31 Jul 2019
project

Synergy_T2SS

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02 May 2019
publication

Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus.

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09 Apr 2019
publication

Structure and Assembly of the Enterohemorrhagic Escherichia coli Type 4 Pilus.

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21 Jan 2019
publication

Functional reconstitution of the type IVa pilus assembly system from enterohaemorrhagic Escherichia coli.

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01 Nov 2018
publication

Tagging the type VI secretion system.

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07 Jun 2018
event

Enterobacterial type IV pili: structure, assembly and molecular function

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23 May 2018
publication

Protein polarization driven by nucleoid exclusion of DnaK(HSP70)-substrate complexes.

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18 Jan 2018
publication

Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions.

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01 Jan 2018
publication

Analysis of Bacterial Pilus Assembly by Shearing and Immunofluorescence Microscopy.

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09 Oct 2017
publication

Structure of the calcium-dependent type 2 secretion pseudopilus.

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01 Oct 2017
publication

1H, 15N and 13C resonance assignments and secondary structure of PulG, the major pseudopilin from Klebsiella oxytoca type 2 secretion system.

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01 Jul 2017
publication

The trans-envelope architecture and function of the type 2 secretion system: new insights raising new questions.

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31 May 2017
publication

Tracking Proteins Secreted by Bacteria: What’s in the Toolbox?

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21 May 2017
publication

Prepore Stability Controls Productive Folding of the BAM-independent Multimeric Outer Membrane Secretin PulD.

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21 May 2017
publication

Polar N-terminal Residues Conserved in Type 2 Secretion Pseudopilins Determine Subunit Targeting and Membrane Extraction Steps during Fibre Assembly

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17 Apr 2017
publication

Polar N-terminal Residues Conserved in Type 2 Secretion Pseudopilins Determine Subunit Targeting and Membrane Extraction Steps during Fibre Assembly.

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06 Jan 2017
publication

Prepore Stability Controls Productive Folding of the BAM-independent Multimeric Outer Membrane Secretin PulD.

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05 Jul 2016
publication

Pseudopilin residue E5 is essential for recruitment by the type 2 secretion system assembly platform.

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06 Jan 2016
news

The pullulanase secretion signal

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10 Dec 2015
publication

Structural Basis of Pullulanase Membrane Binding and Secretion Revealed by X-Ray Crystallography, Molecular Dynamics and Biochemical Analysis

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04 Sep 2015
project

Type II protein secretion mechanism

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22 Jul 2015
project

FiberSpace

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11 May 2015
team

Macromolecular Systems

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11 May 2015
team

Biochemistry of Macromolecular Interactions

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27 Mar 2014
publication

Distinct docking and stabilization steps of the Pseudopilus conformational transition path suggest rotational assembly of type IV pilus-like fibers

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03 Jan 2014
publication

Type II secretion system: a magic beanstalk or a protein escalator

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27 Mar 2013
publication

The type II secretion system – a dynamic fiber assembly nanomachine

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15 Dec 2012
publication

¹H, ¹⁵N and ¹³C resonance assignments of PpdD, a type IV pilin from enterohemorrhagic Escherichia coli

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25 Sep 2012
publication

Heterologous assembly of type IV pili by a type II secretion system reveals the role of minor pilins in assembly initiation

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09 Dec 2011
publication

Minor pseudopilin self-assembly primes type II secretion pseudopilus elongation

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27 Nov 2010
publication

Modeling pilus structures from sparse data

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02 Jul 2010
publication

Detailed structural and assembly model of the type II secretion pilus from sparse data

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17 Apr 2009
publication

The haloprotease CPI produced by the moderately halophilic bacterium Pseudoalteromonas ruthenica is secreted by the type II secretion pathway

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28 Jul 2008
publication

Spx mediates oxidative stress regulation of the methionine sulfoxide reductases operon in Bacillus subtilis

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10 Jan 2008
publication

Cytoplasmic targeting of IpaC to the bacterial pole directs polar type III secretion in Shigella

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01 Nov 2007
publication

Intestinal adherence associated with type IV pili of enterohemorrhagic Escherichia coli O157:H7

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08 Dec 2006
publication

Signal recognition particle-dependent inner membrane targeting of the PulG Pseudopilin component of a type II secretion system

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01 Apr 2006
publication

Green fluorescent chimeras indicate nonpolar localization of pullulanase secreton components PulL and PulM

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01 Oct 2005
publication

Towards the identification of type II secretion signals in a nonacylated variant of pullulanase from Klebsiella oxytoca

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01 Apr 2004
publication

Getting out: protein traffic in prokaryotes

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15 Dec 2000
publication

Expression of the endogenous type II secretion pathway in Escherichia coli leads to chitinase secretion

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01 Mar 2000
publication

The ChiA (YheB) protein of Escherichia coli K-12 is an endochitinase whose gene is negatively controlled by the nucleoid-structuring protein H-NS

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15 Dec 1999
publication

DNA region responsible for transcriptional regulation of the Escherichia coli penicillin amidase (pac) gene by CRP and PAA

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01 Apr 1998
publication

Protein secretion in Escherichia coli K-12: dead or alive?

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01 Feb 1998
publication

A second prepilin peptidase gene in Escherichia coli K-12

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11 Jun 1997
publication

Recent progress and future directions in studies of the main terminal branch of the general secretory pathway in Gram-negative bacteria–a review

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01 Jan 1997
publication

Pullulanase: model protein substrate for the general secretory pathway of gram-negative bacteria

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01 Oct 1996
publication

Escherichia coli SecB stimulates export without maintaining export competence of ribose-binding protein signal sequence mutants

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01 Jun 1996
publication

The cryptic general secretory pathway (gsp) operon of Escherichia coli K-12 encodes functional proteins

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01 Dec 1993
publication

On the puzzling arrangement of the asymmetric MalT-binding sites in the MalT-dependent promoters

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01 Jul 1993
publication

prlA suppression of defective export of maltose-binding protein in secB mutants of Escherichia coli

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01 Apr 1993
publication

A mutation of Escherichia coli SecA protein that partially compensates for the absence of SecB

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01 Apr 1993
publication

Highly selective binding of nascent polypeptides by an Escherichia coli chaperone protein in vivo

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