Timeline

Nathalie Aulner
Head of Facility
24 Apr 2024
publication

Staying on track – Keeping things running in a high-end scientific imaging core facility.

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01 Apr 2024
publication

A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection.

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16 Mar 2024
publication

An equine iPSC-based phenotypic screening platform identifies pro- and anti-viral molecules against West Nile virus.

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31 Jul 2023
event

Inauguration new BSL2 imaging lab

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24 Feb 2023
event

Symposium and Workshop “Pushing the frontiers of dynamic imaging”

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23 Jun 2022
event

Open Microscopy Symposium

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09 May 2022
event

Combination of spectroscopy with microscopy enables new dimensions in quantitative biology – Leonel Malacrida, IP Montevideo

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15 Mar 2022
publication

A Role for Taok2 in Listeria monocytogenes Vacuolar Escape.

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07 Dec 2021
news

New two-photon microscope open for new projects at Photonic Bio Imaging Facility 

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07 Dec 2021
news

New Super Resolution microscope open for new projects at Photonic Bio Imaging at PBI

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18 Nov 2021
event

CANCELLED – Demonstration Aquifer Imaging Machine

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02 Jul 2021
publication

LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images.

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17 May 2021
program_project

Advanced Light Microscopy initiative

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19 Feb 2021
event

C2RT TECHNOLOGICAL SEMINARS : The ACQUIFER Imaging Machine

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01 Jan 2021
publication

Corrigendum: Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.

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14 Dec 2020
news

Season Greetings 2023/24

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11 Feb 2020
publication

Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response.

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01 Jan 2020
publication

Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.

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12 Nov 2019
tool

Single Cell Phenotyping – Microscopy

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01 Oct 2019
news

PBI User satisfaction Survey 2019

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10 Sep 2019
news

Pascal

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10 Jul 2019
news

SUMMER 2019 @ PBI

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09 Jul 2019
publication

Author Correction: Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening.

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05 Jun 2019
publication

Next-Generation Phenotypic Screening in Early Drug Discovery for Infectious Diseases

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24 Jan 2019
publication

Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening.

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13 Jun 2018
news

Demonstration of new Light-Sheet microscope: Alpha3 light sheet microscope

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13 Jun 2018
news

Thursday, July 12 : Presentation from Zeiss compagny on “Machine learning, intelligent imaging, multi-scale correlative: the innovations of the ZEN software to gain autonomy”

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01 Jun 2018
publication

Fluorescence imaging host pathogen interactions: fifteen years benefit of hindsight….

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27 Feb 2018
event

Rémi Galland, University of Bordeaux, Interdisciplinary Institute for Neurosciences

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27 Feb 2018
event

Alain Chedotal, Institut de la Vision, Paris

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27 Feb 2018
event

Fluorescence Microscopy Workshop III/on cutting-technologies

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27 Feb 2018
event

Fluorescence Microscopy Workshop III/on cutting-edge technologies

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05 Dec 2017
news

Microscopy Core OpenDesk

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17 Aug 2017
team

Photonic BioImaging (UTechS PBI)

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01 Jan 2017
publication

Assessing Vacuolar Escape of Listeria Monocytogenes

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12 Sep 2016
publication

Screening out irrelevant cell-based models of disease.

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01 May 2016
publication

From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.

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10 Apr 2016
tool

Dual microscopy assay to discriminate Listeria cellular entry & vacuolar escape

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23 Oct 2015
publication

A Dual Microscopy-Based Assay To Assess Listeria monocytogenes Cellular Entry and Vacuolar Escape

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07 Sep 2015
project

FP7 Targeting the Leishmania kinome for the development of novel anti-parasitic strategies (LeishDrug)

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07 Sep 2015
project

PTR 496 – Investigating the reciprocal relationship between macrophage inflammasome activity and intracellular Leishmania infection

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08 Oct 2014
publication

Shigella subverts the host recycling compartment to rupture its vacuole

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01 Jan 2014
publication

Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.

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21 Oct 2013
publication

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors

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04 Apr 2013
publication

High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery

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16 Dec 2009
publication

HIV-1 Nef inhibits ruffles, induces filopodia, and modulates migration of infected lymphocytes

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12 Oct 2009
publication

Intracellular bacteria encode inhibitory SNARE-like proteins

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30 Jan 2009
publication

Potent inhibitors of Huntingtin protein aggregation in a cell-based assay

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01 Jan 2009
publication

Cell-based assays to probe the ERK MAP kinase pathway in endothelial cells

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25 Dec 2008
publication

Discovery of novel small molecule cell type-specific enhancers of NF-kappaB nuclear translocation

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30 Oct 2007
publication

Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFkappaB activity within two separate high-throughput screens of NFkappaB activation

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01 Jan 2006
publication

Cell-based assays using primary endothelial cells to study multiple steps in inflammation

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01 Jun 2005
publication

Sequence characteristics of functional siRNAs

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01 Mar 2005
publication

Bacterial and host factors implicated in nasal carriage of methicillin-resistant Staphylococcus aureus in mice

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15 Dec 2004
publication

CXCR4-tropic HIV-1 envelope glycoprotein functions as a viral chemokine in unstimulated primary CD4+ T lymphocytes

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01 Apr 2004
publication

Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene

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16 Dec 2002
publication

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle.

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15 Jul 2002
publication

Modification of position-effect variegation by competition for binding to Drosophila satellites

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01 Feb 2002
publication

The AT-hook protein D1 is essential for Drosophila melanogaster development and is implicated in position-effect variegation

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15 May 2000
publication

Induction of early transcription in one-cell mouse embryos by microinjection of the nonhistone chromosomal protein HMG-I

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01 Oct 1999
publication

The Drosophila poly(A)-binding protein II is ubiquitous throughout Drosophila development and has the same function in mRNA polyadenylation as its bovine homolog in vitro

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