Timeline

Iuliana Ene

Head of Structure

18 Nov 2024

publication

Hidden allies: how extracellular vesicles drive biofilm formation, stress adaptation, and host-immune interactions in human fungal pathogens.

19 Aug 2024

publication

An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicans.

01 Aug 2024

publication

Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans.

12 Jul 2024

event

3rd Drug Discovery & Screening Symposium – “Innovative Therapeutics: Small Molecules and Biologics in Modern Medicine” – an ATC-DDS initiative

23 Apr 2024

publication

Identification of an active RNAi pathway in Candida albicans.

12 Apr 2024

event

Call for abstracts & Register ! “Tackling antibacterial and antifungal resistant infections from disease to innovative therapies” – an international AMR symposium

14 Mar 2024

publication

Approaches for identifying and measuring heteroresistance in azole-susceptible Candida isolates.

01 Mar 2024

publication

The hyphal-specific toxin candidalysin promotes fungal gut commensalism.

31 Aug 2023

publication

Coregulation of extracellular vesicle production and fluconazole susceptibility in Cryptococcus neoformans.

01 Aug 2023

publication

Azole potentiation in Candida species.

16 Jun 2023

publication

Small molecules restore azole activity against drug-tolerant and drug-resistant Candida isolates.

13 Jun 2023

publication

Coregulation of extracellular vesicle production and fluconazole susceptibility in Cryptococcus neoformans

14 Mar 2023

publication

Aneuploidy and gene dosage regulate filamentation and host colonization by Candida albicans.

04 Nov 2022

publication

The future of fungi: threats and opportunities.

17 May 2022

publication

Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity.

21 Dec 2021

publication

Candida albicans Isolates 529L and CHN1 Exhibit Stable Colonization of the Murine Gastrointestinal Tract.

09 Nov 2021

event

Mycology department seminar – Duncan Wilson “The fungal zincophore as a key determinant in zinc scavenging and immunopathology”

26 Jul 2021

news

ANR PRC call : Congratulations to Guilhem Janbon, Iuliana Ene and Alexandre Alanio for their successful project proposal “ResistEV”

23 Jun 2021

publication

The Interplay Between Neutral and Adaptive Processes Shapes Genetic Variation During Candida Species Evolution

09 Apr 2021

publication

Adaptation to the dietary sugar D-tagatose via genome instability in polyploid Candida albicans cells.

09 Feb 2021

publication

Comparative genomics of white and opaque cell states supports an epigenetic mechanism of phenotypic switching in Candida albicans.

01 Feb 2021

publication

Comparative genomics of white and opaque cell states supports an epigenetic mechanism of phenotypic switching in Candida albicans

18 Jan 2021

team

Fungal Heterogeneity

01 May 2020

publication

Short-term evolution strategies for host adaptation and drug escape in human fungal pathogens.

01 Jan 2019

publication

Hemizygosity Enables a Mutational Transition Governing Fungal Virulence and Commensalism.

01 Jan 2019

publication

Mechanisms of genome evolution in Candida albicans.

25 Jun 2018

publication

Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia.

01 Jan 2018

publication

Global analysis of mutations driving microevolution of a heterozygous diploid fungal pathogen.

01 Jan 2016

publication

Systematic Genetic Screen for Transcriptional Regulators of the Candida albicans White-Opaque Switch

01 Jan 2016

publication

Phenotypic Profiling Reveals that Candida albicans Opaque Cells Represent a Metabolically Specialized Cell State Compared to Default White Cells.

28 Jul 2015

publication

Cell Wall Remodeling Enzymes Modulate Fungal Cell Wall Elasticity and Osmotic Stress Resistance

04 Sep 2014

publication

Metabolism in fungal pathogenesis

01 Apr 2014

publication

The cryptic sexual strategies of human fungal pathogens

25 Feb 2014

publication

Integration of metabolism with virulence in Candida albicans

01 Jan 2014

publication

Stress adaptation in a pathogenic fungus

01 Jan 2013

publication

Growth of Candida albicans cells on the physiologically relevant carbon source lactate affects their recognition and phagocytosis by immune cells

01 Nov 2012

publication

Carbon source-induced reprogramming of the cell wall proteome and secretome modulates the adherence and drug resistance of the fungal pathogen Candida albicans

01 Sep 2012

publication

Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen

01 Dec 2009

publication

A little guide for advanced search:

Hidden allies: how extracellular vesicles drive biofilm formation, stress adaptation, and host-immune interactions in human fungal pathogens.

An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicans.

Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans.

3rd Drug Discovery & Screening Symposium – “Innovative Therapeutics: Small Molecules and Biologics in Modern Medicine” – an ATC-DDS initiative

Identification of an active RNAi pathway in Candida albicans.

Call for abstracts & Register ! “Tackling antibacterial and antifungal resistant infections from disease to innovative therapies” – an international AMR symposium

Approaches for identifying and measuring heteroresistance in azole-susceptible Candida isolates.

The hyphal-specific toxin candidalysin promotes fungal gut commensalism.

Coregulation of extracellular vesicle production and fluconazole susceptibility in Cryptococcus neoformans.

Azole potentiation in Candida species.

Small molecules restore azole activity against drug-tolerant and drug-resistant Candida isolates.

Coregulation of extracellular vesicle production and fluconazole susceptibility in Cryptococcus neoformans

Aneuploidy and gene dosage regulate filamentation and host colonization by Candida albicans.

The future of fungi: threats and opportunities.

Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity.

Candida albicans Isolates 529L and CHN1 Exhibit Stable Colonization of the Murine Gastrointestinal Tract.

Mycology department seminar – Duncan Wilson “The fungal zincophore as a key determinant in zinc scavenging and immunopathology”

ANR PRC call : Congratulations to Guilhem Janbon, Iuliana Ene and Alexandre Alanio for their successful project proposal “ResistEV”

The Interplay Between Neutral and Adaptive Processes Shapes Genetic Variation During Candida Species Evolution

Adaptation to the dietary sugar D-tagatose via genome instability in polyploid Candida albicans cells.

Comparative genomics of white and opaque cell states supports an epigenetic mechanism of phenotypic switching in Candida albicans.

Comparative genomics of white and opaque cell states supports an epigenetic mechanism of phenotypic switching in Candida albicans

Fungal Heterogeneity

Short-term evolution strategies for host adaptation and drug escape in human fungal pathogens.

Hemizygosity Enables a Mutational Transition Governing Fungal Virulence and Commensalism.

Mechanisms of genome evolution in Candida albicans.

Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia.

Global analysis of mutations driving microevolution of a heterozygous diploid fungal pathogen.

Systematic Genetic Screen for Transcriptional Regulators of the Candida albicans White-Opaque Switch

Phenotypic Profiling Reveals that Candida albicans Opaque Cells Represent a Metabolically Specialized Cell State Compared to Default White Cells.

Cell Wall Remodeling Enzymes Modulate Fungal Cell Wall Elasticity and Osmotic Stress Resistance

Metabolism in fungal pathogenesis

The cryptic sexual strategies of human fungal pathogens

Integration of metabolism with virulence in Candida albicans

Stress adaptation in a pathogenic fungus

Growth of Candida albicans cells on the physiologically relevant carbon source lactate affects their recognition and phagocytosis by immune cells

Carbon source-induced reprogramming of the cell wall proteome and secretome modulates the adherence and drug resistance of the fungal pathogen Candida albicans

Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen

Hwp1 and related adhesins contribute to both mating and biofilm formation in Candida albicans