Ligne de temps

Olivier Helynck
Technicien(ne)
30 sept. 2023
publication

Novel Antiviral Molecules against Ebola Virus Infection.

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24 janv. 2023
publication

Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands.

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11 oct. 2022
publication

Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism.

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21 juil. 2021
publication

SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction.

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21 mai 2021
publication

Prevalence of SARS-CoV-2 antibodies in France: results from nationwide serological surveillance.

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03 mai 2021
team

Plateforme d’Innovation et de Développement de Tests Diagnostiques

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01 janv. 2021
publication

High seroprevalence but short-lived immune response to SARS-CoV-2 infection in Paris.

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02 févr. 2019
publication

First-in-class allosteric inhibitors of bacterial IMPDHs

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25 mai 2018
publication

A Novel Polyaminocarboxylate Compound To Treat Murine Pulmonary Aspergillosis by Interfering with Zinc Metabolism

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23 nov. 2017
publication

Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT

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28 août 2017
publication

Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in Mycobacterium smegmatis

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14 août 2017
publication

Original chemical series of pyrimidine biosynthesis inhibitors that boost the antiviral interferon response

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03 sept. 2015
project

Inhibitors of Pseudomonas aeruginosa IMPDH

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28 juil. 2015
project

Alkoxypyrazoles, inhibitors of dihydroorotate dehydrogenase (DHODH)

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22 juil. 2015
project

Inosine-5′-monophosphate dehydrogenase

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30 juin 2015
publication

Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)

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06 janv. 2015
publication

Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH)

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05 mai 2014
publication

High-throughput screening for broad-spectrum chemical inhibitors of RNA viruses

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03 oct. 2013
publication

Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity

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01 févr. 2013
publication

Synergy of the antibiotic colistin with echinocandin antifungals in Candida species

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18 oct. 2011
publication

Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase

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