Timeline

Olivier Helynck
Technician
07 Jul 2021
publication

SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction.

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01 Jan 2021
publication

High seroprevalence but short-lived immune response to SARS-CoV-2 infection in Paris.

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02 Feb 2019
publication

First-in-class allosteric inhibitors of bacterial IMPDHs

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02 Jan 2019
team

Organic Chemistry

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25 May 2018
publication

A Novel Polyaminocarboxylate Compound To Treat Murine Pulmonary Aspergillosis by Interfering with Zinc Metabolism

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23 Nov 2017
publication

Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT

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28 Aug 2017
publication

Nitazoxanide Analogs Require Nitroreduction for Antimicrobial Activity in Mycobacterium smegmatis

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14 Aug 2017
publication

Original chemical series of pyrimidine biosynthesis inhibitors that boost the antiviral interferon response

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14 Dec 2015
publication

The Toxicity of a Novel Antifungal Compound Is Modulated by Endoplasmic Reticulum-Associated Protein Degradation Components

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03 Sep 2015
project

Inhibitors of Pseudomonas aeruginosa IMPDH

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28 Jul 2015
project

Alkoxypyrazoles, inhibitors of dihydroorotate dehydrogenase (DHODH)

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22 Jul 2015
project

Inosine-5′-monophosphate dehydrogenase

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16 Jul 2015
team

Group: Biochemistry and screening

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30 Jun 2015
publication

Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)

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05 Jun 2015
team

Chemogenomic and Biological Screening Platform (PF-CCB)

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06 Feb 2015
publication

[Stimulation of the antiviral innate immune response by pyrimidine biosynthesis inhibitors: a surprise of phenotypic screening]

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06 Jan 2015
publication

Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH)

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05 May 2014
publication

High-throughput screening for broad-spectrum chemical inhibitors of RNA viruses

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03 Oct 2013
publication

Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity

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01 Feb 2013
publication

Synergy of the antibiotic colistin with echinocandin antifungals in Candida species

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18 Oct 2011
publication

Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase

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