Ligne de temps
Marcel Hollenstein
Responsable de Structure
20 nov. 2023
publication
Expedient synthesis of l-heptose derived septacidin building blocks from l-glucose
Lire plus15 nov. 2023
01 nov. 2023
publication
Increasing the π-Expansive Ligands in Ruthenium(II) Polypyridyl Complexes: Synthesis, Characterization, and Biological Evaluation for Photodynamic Therapy Applications
Lire plus28 août 2023
15 mars 2023
project
CoVariant – Comprendre les déterminants de l’immunité muqueuse et optimiser le diagnostic de l’infection aux variants du SARS-CoV-2
Lire plus01 janv. 2023
publication
Towards the controlled enzymatic synthesis of LNA containing oligonucleotides.
Lire plus15 déc. 2022
30 nov. 2022
publication
High-Content RNAi Phenotypic Screening Unveils the Involvement of Human Ubiquitin-Related Enzymes in Late Cytokinesis
Lire plus26 oct. 2022
publication
Ferrocene as a potential electrochemical reporting surrogate of abasic sites in DNA
Lire plus11 sept. 2022
project
Energir: Comprendre les mécanismes moléculaires d’acquisition du fer chez les bactéries à Gram-négatif, par une approche intégrative
Lire plus26 août 2022
26 août 2022
publication
Benzoyl and pivaloyl as efficient protecting groups for controlled enzymatic synthesis of DNA and XNA oligonucleotides
Lire plus01 juin 2022
publication
Evaluation of 3′-phosphate as a transient protecting group for controlled enzymatic synthesis of DNA and XNA oligonucleotides
Lire plus01 juin 2022
publication
Evaluation of 3′-phosphate as a transient protecting group for controlled enzymatic synthesis of DNA and XNA oligonucleotides.
Lire plus08 mars 2022
05 janv. 2022
publication
A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy
Lire plus18 nov. 2021
31 oct. 2021
publication
A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy
Lire plus01 sept. 2021
publication
A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy
Lire plus07 juil. 2021
publication
Towards the enzymatic synthesis of phosphorothioate containing LNA oligonucleotides
Lire plus29 avr. 2021
27 avr. 2021
14 avr. 2021
22 oct. 2020
publication
Enzymatic Formation of an Artificial Base Pair Using a Modified Purine Nucleoside Triphosphate
Lire plus16 juil. 2020
publication
Enzymatic Construction of Artificial Base Pairs: The Effect of Metal Shielding
Lire plus06 juil. 2020
publication
Evolution of abiotic cubane chemistries in a nucleic acid aptamer allows selective recognition of a malaria biomarker.
Lire plus15 mai 2020
07 mai 2020
20 mars 2020
19 mars 2020
publication
Self‐Assembly of DNA and RNA Building Blocks Explored by Nitrogen‐14 NMR Crystallography: Structure and Dynamics
Lire plus25 févr. 2020
30 janv. 2020
publication
Ruthenium-initiated polymerization of lactide: a route to remarkable cellular uptake for photodynamic therapy of cancer.
Lire plus30 janv. 2020
publication
Ruthenium-initiated polymerization of lactide: a route to remarkable cellular uptake for photodynamic therapy of cancer
Lire plus23 déc. 2019
publication
Enzymatic Formation of an Artificial Base Pair Using a Modified Adenine Nucleoside Triphosphate
Lire plus13 déc. 2019
publication
On the Enzymatic Formation of Metal Base Pairs with Thiolated and pKa-Perturbed Nucleotides
Lire plus09 sept. 2019
event
Department of Structural biology and chemistry seminar: Dr; David M. Perrin, Selection of RNaseA-mimicking DNAzymes with amines, imidazoles, and guanidines that cleave RNA: from unnatural aptamer selections unto to the origin of life
Lire plus04 sept. 2019
event
Department of Structural Biology and Chemistry: David M. Perrin, Selection of RNaseA-mimicking DNAzymes with amines, imidazoles, and guanidines that cleave RNA: from unnatural aptamer selections unto to the origin of life
Lire plus19 août 2019
publication
Compatibility of 5-ethynyl-2’F-ANA UTP with in vitro selection for the generation of base-modified, nuclease resistant aptamers
Lire plus14 juil. 2019
17 mai 2019
publication
Synthesis and Enzymatic Characterization of Sugar-Modified Nucleoside Triphosphate Analogs
Lire plus15 mai 2019
29 mars 2019
publication
Terminal Deoxynucleotidyl Transferase in the Synthesis and Modification of Nucleic Acids
Lire plus02 févr. 2019
publication
Towards the enzymatic formation of artificial metal base pairs with a carboxy-imidazole-modified nucleotide
Lire plus07 déc. 2018
07 déc. 2018
event
Seminar of the Structural Biology and Chemistry department: Mélanie Etheve-Quelquejeu
Lire plus21 oct. 2018
22 août 2018
22 août 2018
23 juil. 2018
publication
Shaping Rolling Circle Amplification Products into DNA Nanoparticles by Incorporation of Modified Nucleotides and Their Application to In Vitro and In Vivo Delivery of a Photosensitizer
Lire plus23 juil. 2018
06 avr. 2018
04 avr. 2018
24 janv. 2018
19 juin 2017
01 mai 2017
17 mars 2017
04 févr. 2017
publication
New synthetic route to ethynyl-dUTP: A means to avoid formation of acetyl and chloro vinyl base-modified triphosphates that could poison SELEX experiments
Lire plus05 déc. 2016
publication
Rolling circle amplification with chemically modified nucleoside triphosphates
Lire plus12 janv. 2016
20 nov. 2015
14 oct. 2015
publication
Generation of long, fully modified, and serum-resistant oligonucleotides by rolling circle amplification
Lire plus14 sept. 2015
01 mai 2015
publication
Probing the effect of minor groove interactions on the catalytic efficiency of DNAzymes 8-17 and 10-23
Lire plus25 janv. 2015
publication
A method for selecting modified DNAzymes without the use of modified DNA as a template in PCR
Lire plus17 juil. 2014
publication
Synthesis and biochemical characterization of tricyclothymidine triphosphate (tc-TTP)
Lire plus03 avr. 2014
02 juil. 2013
publication
Deoxynucleoside triphosphates bearing histamine, carboxylic acid, and hydroxyl residues–synthesis and biochemical characterization
Lire plus13 mars 2013
publication
Toward the combinatorial selection of chemically modified DNAzyme RNase A mimics active against all-RNA substrates
Lire plus15 nov. 2012
publication
Nucleoside triphosphates–building blocks for the modification of nucleic acids
Lire plus20 sept. 2012
publication
Synthesis of deoxynucleoside triphosphates that include proline, urea, or sulfonamide groups and their polymerase incorporation into DNA
Lire plus05 mai 2012
13 juin 2011
10 févr. 2011
publication
Protein-inspired modified DNAzymes: dramatic effects of shortening side-chain length of 8-imidazolyl modified deoxyadenosines in selecting RNaseA mimicking DNAzymes
Lire plus01 janv. 2011
17 août 2009
publication
A DNAzyme with three protein-like functional groups: enhancing catalytic efficiency of M2+-independent RNA cleavage
Lire plus19 janv. 2009
publication
A self-cleaving DNA enzyme modified with amines, guanidines and imidazoles operates independently of divalent metal cations (M2+)
Lire plus01 janv. 2008
01 janv. 2008
15 avr. 2005
publication
Fluorinated olefinic peptide nucleic acid: synthesis and pairing properties with complementary DNA
Lire plus29 mai 2003
publication
Synthesis and incorporation into PNA of fluorinated olefinic PNA (F-OPA) monomers
Lire plus01 mai 2003
08 juin 2000
publication