Ligne de temps

Pablo Guardado-Calvo
Responsable de Structure
19 juil. 2024
publication

Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2.

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01 janv. 2024
publication

Production and Purification of Hantavirus Glycoproteins in Drosophila melanogaster S2 Cells.

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08 déc. 2023
publication

Neutralization Determinants on Poxviruses

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24 juil. 2023
publication

Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection.

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14 juin 2023
publication

Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody.

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28 mars 2023
publication

Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein.

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27 mars 2023
publication

Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies.

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13 janv. 2023
publication

A Search for Tick-Associated, Bronnoya-like Virus Spillover into Sheep

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04 janv. 2023
team

Biologie structurale des maladies infectieuses

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04 juil. 2022
publication

Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.

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17 juin 2022
news

New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2

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16 mars 2022
publication

Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses.

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07 janv. 2022
publication

Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.

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01 janv. 2022
publication

Editorial: Influence of Protein-Protein Interactions (PPIs) on the Outcome of Viral Infections.

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09 déc. 2021
publication

The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses.

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26 nov. 2021
publication

The Viral Class II Membrane Fusion Machinery: Divergent Evolution from an Ancestral Heterodimer.

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01 oct. 2021
publication

The surface glycoproteins of hantaviruses.

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01 sept. 2021
publication

Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling.

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01 janv. 2021
publication

Generation of plasma cells and CD27-IgD- B cells during hantavirus infection is associated with distinct pathological findings.

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15 oct. 2020
publication

The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.

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21 avr. 2020
publication

Multimeric single-domain antibody complexes protect against bunyavirus infections.

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10 avr. 2020
project

CORONABODIES

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10 juin 2019
publication

Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface.

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20 févr. 2019
publication

Orthobunyavirus spike architecture and recognition by neutralizing antibodies.

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01 janv. 2019
publication

Reverse Immunology Approach to Define a New HIV-gp41-Neutralizing Epitope.

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01 nov. 2018
publication

Protocadherin-1 is essential for cell entry by New World hantaviruses.

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01 janv. 2018
publication

Structure-Function Dissection of Pseudorabies Virus Glycoprotein B Fusion Loops.

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03 nov. 2017
publication

A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion.

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23 mai 2017
publication

Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope.

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01 janv. 2017
publication

The Envelope Proteins of the Bunyavirales.

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01 oct. 2016
publication

Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc.

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02 avr. 2015
publication

Recognition determinants of broadly neutralizing human antibodies against dengue viruses.

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01 oct. 2014
publication

Robust and low cost uniform (15)N-labeling of proteins expressed in Drosophila S2 cells and Spodoptera frugiperda Sf9 cells for NMR applications.

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01 oct. 2012
publication

High-resolution structures of Thermus thermophilus enoyl-acyl carrier protein reductase in the apo form, in complex with NAD+ and in complex with NAD+ and triclosan.

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01 oct. 2010
publication

Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains.

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14 janv. 2010
publication

Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues.

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01 nov. 2009
publication

Crystallization of the head and galectin-like domains of porcine adenovirus isolate NADC-1 fibre.

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01 mars 2009
publication

Crystallographic structure of the alpha-helical triple coiled-coil domain of avian reovirus S1133 fibre.

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01 nov. 2008
publication

Crystal structure of the avian reovirus inner capsid protein sigmaA.

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01 sept. 2007
publication

Structure of the C-terminal head domain of the fowl adenovirus type 1 long fiber.

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01 mai 2007
publication

Crystallization of the avian reovirus double-stranded RNA-binding and core protein sigmaA.

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01 mai 2006
publication

Crystallization of the C-terminal head domain of the avian adenovirus CELO long fibre.

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18 nov. 2005
publication

Structure of the carboxy-terminal receptor-binding domain of avian reovirus fibre sigmaC.

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01 juil. 2005
publication

Crystallization of the C-terminal globular domain of avian reovirus fibre.

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