Ligne de temps
Pablo Guardado-Calvo
Responsable de Structure
18 août 2025
publication
Structural basis of poxvirus fusion regulation and anti-A16/G9 antibody-mediated neutralization and protection.
Lire plus01 juil. 2025
publication
Modulation of SARS-CoV-2 spike binding to ACE2 through conformational selection.
Lire plus15 avr. 2025
publication
Monkeypox Virus Infection Stimulates a More Robust and Durable Neutralizing Antibody Response Compared to Modified Vaccinia Virus Ankara Vaccination.
Lire plus06 mars 2025
publication
On the role of VP3-PI3P interaction in birnavirus endosomal membrane targeting.
Lire plus01 févr. 2025
publication
Disruption of deoxyribonucleotide triphosphate biosynthesis leads to RAS proto-oncogene activation and perturbation of mitochondrial metabolism.
Lire plus01 févr. 2025
publication
Disruption of deoxyribonucleotide triphosphate biosynthesis leads to RAS proto-oncogene activation and perturbation of mitochondrial metabolism
Lire plus23 janv. 2025
publication
Antiviral activity of tecovirimat against monkeypox virus clades 1a, 1b, 2a, and 2b.
Lire plus01 janv. 2025
publication
Puumala orthohantavirus: prevalence, biology, disease, animal models and recent advances in therapeutics development and structural biology.
Lire plus01 janv. 2025
publication
Structural insights into tecovirimat antiviral activity and poxvirus resistance.
Lire plus19 juil. 2024
publication
Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2.
Lire plus01 janv. 2024
publication
Production and Purification of Hantavirus Glycoproteins in Drosophila melanogaster S2 Cells.
Lire plus08 déc. 2023
24 juil. 2023
publication
Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection.
Lire plus14 juin 2023
publication
Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody.
Lire plus28 mars 2023
publication
Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein.
Lire plus27 mars 2023
publication
Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies.
Lire plus13 janv. 2023
04 janv. 2023
01 janv. 2023
publication
Diversity of Viruses in Ixodes ricinus in Europe including Novel and Potential Arboviruses.
Lire plus04 juil. 2022
publication
Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
Lire plus17 juin 2022
news
New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2
Lire plus16 mars 2022
publication
Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses.
Lire plus07 janv. 2022
publication
Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.
Lire plus01 janv. 2022
publication
Editorial: Influence of Protein-Protein Interactions (PPIs) on the Outcome of Viral Infections.
Lire plus09 déc. 2021
publication
The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses.
Lire plus26 nov. 2021
publication
The Viral Class II Membrane Fusion Machinery: Divergent Evolution from an Ancestral Heterodimer.
Lire plus01 oct. 2021
01 sept. 2021
publication
Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling.
Lire plus01 janv. 2021
publication
Generation of plasma cells and CD27-IgD- B cells during hantavirus infection is associated with distinct pathological findings.
Lire plus15 oct. 2020
21 avr. 2020
publication
Multimeric single-domain antibody complexes protect against bunyavirus infections.
Lire plus10 avr. 2020
10 juin 2019
publication
Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface.
Lire plus20 févr. 2019
publication
Orthobunyavirus spike architecture and recognition by neutralizing antibodies.
Lire plus01 janv. 2019
01 nov. 2018
01 janv. 2018
publication
Structure-Function Dissection of Pseudorabies Virus Glycoprotein B Fusion Loops.
Lire plus03 nov. 2017
publication
A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion.
Lire plus23 mai 2017
publication
Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope.
Lire plus01 janv. 2017
01 oct. 2016
publication
Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc.
Lire plus02 avr. 2015
publication
Recognition determinants of broadly neutralizing human antibodies against dengue viruses.
Lire plus01 oct. 2014
publication
Robust and low cost uniform (15)N-labeling of proteins expressed in Drosophila S2 cells and Spodoptera frugiperda Sf9 cells for NMR applications.
Lire plus01 oct. 2012
publication
High-resolution structures of Thermus thermophilus enoyl-acyl carrier protein reductase in the apo form, in complex with NAD+ and in complex with NAD+ and triclosan.
Lire plus01 oct. 2010
publication
Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains.
Lire plus14 janv. 2010
publication
Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues.
Lire plus01 nov. 2009
publication
Crystallization of the head and galectin-like domains of porcine adenovirus isolate NADC-1 fibre.
Lire plus01 mars 2009
publication
Crystallographic structure of the alpha-helical triple coiled-coil domain of avian reovirus S1133 fibre.
Lire plus01 nov. 2008
01 sept. 2007
publication
Structure of the C-terminal head domain of the fowl adenovirus type 1 long fiber.
Lire plus01 mai 2007
publication
Crystallization of the avian reovirus double-stranded RNA-binding and core protein sigmaA.
Lire plus01 mai 2006
publication
Crystallization of the C-terminal head domain of the avian adenovirus CELO long fibre.
Lire plus18 nov. 2005
publication
Structure of the carboxy-terminal receptor-binding domain of avian reovirus fibre sigmaC.
Lire plus01 juil. 2005