Ligne de temps

Laleh Majlessi
Directeur(trice) de Recherche
02 avr. 2024
publication

A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: candidate selection in a preclinical murine model.

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07 sept. 2023
publication

Full eradication of pre-clinical human papilloma virus-induced tumors by a lentiviral vaccine.

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18 avr. 2023
publication

Mice Humanized for MHC and hACE2 with High Permissiveness to SARS-CoV-2 Omicron Replication.

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01 janv. 2023
publication

Sec61 blockade therapy overrides resistance to proteasome inhibitors and immunomodulatory drugs in multiple myeloma.

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01 janv. 2023
publication

Preclinical proof of concept of a tetravalent lentiviral T-cell vaccine against dengue viruses.

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21 déc. 2022
publication

Full-Lung Prophylaxis against SARS-CoV-2 by One-Shot or Booster Intranasal Lentiviral Vaccination in Syrian Golden Hamsters

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14 sept. 2022
publication

A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity.

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26 juil. 2022
publication

A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity.

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27 avr. 2022
publication

An intranasal lentiviral booster reinforces the waning mRNA vaccine-induced SARS-CoV-2 immunity that it targets to lung mucosa.

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07 déc. 2021
publication

Brain cross-protection against SARS-CoV-2 variants by a lentiviral vaccine in new transgenic mice.

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29 juil. 2021
team

Laboratoire Commun Pasteur – TheraVectys

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09 avr. 2021
event

Seminar DPT Microbiology “Intranasal Vaccination with a Lentiviral Vector Fully Protects Lungs and Brain against SARS-CoV-2”, Laleh Majlessi

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06 avr. 2021
project

Modeling SARS-CoV-2 infection and immune responses in humanized mouse models

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01 mars 2019
publication

Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers Against Tuberculosis

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11 juil. 2018
publication

Unexpected genomic and phenotypic diversity of Mycobacterium africanum Lineage 5 affects drug resistance, protein secretion and immunogenicity

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18 juin 2018
publication

RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection

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24 avr. 2018
publication

Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors

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17 janv. 2018
publication

Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus

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28 août 2017
publication

Un nouveau concept pour améliorer le vaccin antituberculeux

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14 mars 2017
publication

Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection

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01 févr. 2017
publication

Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis

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01 nov. 2016
publication

The distinct fate of smooth and rough Mycobacterium abscessus variants inside macrophages

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26 sept. 2016
publication

ESX secretion systems: mycobacterial evolution to counter host immunity

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28 juil. 2016
publication

CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection

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31 mai 2016
publication

Perspectives on mycobacterial vacuole-to-cytosol translocation: the importance of cytosolic access

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28 avr. 2016
publication

A unique PE_PGRS protein inhibiting host cell cytosolic defenses and sustaining full virulence of Mycobacterium marinum in multiple hosts

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27 janv. 2016
publication

pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence

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02 déc. 2015
event

EMBO Conference Tuberculosis 2016

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25 nov. 2015
publication

Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis

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10 juin 2015
publication

Mycobacterium tuberculosis Meets the Cytosol: The Role of cGAS in Anti-mycobacterial Immunity

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11 mai 2015
team

Pathogénomique Mycobactérienne Intégrée

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01 mars 2015
publication

Release of mycobacterial antigens

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13 févr. 2015
publication

ESX/type VII secretion systems of mycobacteria: Insights into evolution, pathogenicity and protection

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06 févr. 2015
publication

Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo

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06 janv. 2013
publication

Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis

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19 avr. 2012
publication

Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential

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