Biologie de Plasmodium et Vaccins

Présentation

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Membres

Chetan Chitnis

Responsable de Structure

Responsable

Micheline Guillotte-Blisnick

Ingénieur(e) de Recherche

Christèle Huon

Ingénieur(e) de Recherche

Pallavi Singh

Etudiant(e) en thèse

Maryse Brandt

Personnel Administratif

Kunal More

Post-doctorant(e)

Matthias Wagner

Etudiant(e) en thèse

Anciens Membres

Cidalia Da Agra

Amandine Aoufoussi

Shailja Singh

Aditi Alaganan

Aneesh Vijayan

Undina Guillerm

Marie Demeslay-Gougam

Projet Transversal

Institut Carnot Pasteur MS

Le label Carnot vise à reconnaître la 
capacité de structures de recherche à collaborer avec des partenaires socio-
économiques, notamment des entreprises, tout en renforçant leur visibilité. Un institut Canot (IC) labélisé bénéficie de moyens […]

Publications

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• 2017
  Vijayan A, Mejías-Pérez E, Espinosa DA, Raman SC, Sorzano COS, Zavala F, Esteban M, A Prime/Boost PfCS14K(M)/MVA-sPfCS(M) Vaccination Protocol Generates Robust CD8(+) T Cell and Antibody Responses to Plasmodium falciparum Circumsporozoite Protein and Protects Mice against Malaria, Clin. Vaccine Immunol. 2017 May;24(5).
• 2015
  Chitnis CE, Mukherjee P, Mehta S, Yazdani SS, Dhawan S, Shakri AR, Bharadwaj R, Gupta PK, Hans D, Mazumdar S, Singh B, Kumar S, Pandey G, Parulekar V, Imbault N, Shivyogi P, Godbole G, Mohan K, Leroy O, Singh K, Chauhan VS, Phase I Clinical Trial of a Recombinant Blood Stage Vaccine Candidate for Plasmodium falciparum Malaria Based on MSP1 and EBA175, PLoS ONE 2015;10(4):e0117820.
• 2014
  Dawn A, Singh S, More KR, Siddiqui FA, Pachikara N, Ramdani G, Langsley G, Chitnis CE, The central role of cAMP in regulating Plasmodium falciparum merozoite invasion of human erythrocytes, PLoS Pathog. 2014 Dec;10(12):e1004520.
• 2013
  Vijayan A, Guha D, Ameer F, Kaziri I, Mooney CC, Bennett L, Sureshbabu A, Tonner E, Beattie J, Allan GJ, Edwards J, Flint DJ, IGFBP-5 enhances epithelial cell adhesion and protects epithelial cells from TGFβ1-induced mesenchymal invasion, Int. J. Biochem. Cell Biol. 2013 Dec;45(12):2774-85.
• 2013
  Singh S, More KR, Chitnis CE, Role of calcineurin and actin dynamics in regulated secretion of microneme proteins in Plasmodium falciparum merozoites during erythrocyte invasion, Cell. Microbiol. 2014 Jan;16(1):50-63.
• 2013
  Garg S, Agarwal S, Kumar S, Yazdani SS, Chitnis CE, Singh S, Calcium-dependent permeabilization of erythrocytes by a perforin-like protein during egress of malaria parasites, Nat Commun 2013;4:1736.
• 2012
  Bansal A, Singh S, More KR, Hans D, Nangalia K, Yogavel M, Sharma A, Chitnis CE, Characterization of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) and its role in microneme secretion during erythrocyte invasion, J. Biol. Chem. 2013 Jan;288(3):1590-602.
• 2012
  Vijayan A, Gómez CE, Espinosa DA, Goodman AG, Sanchez-Sampedro L, Sorzano CO, Zavala F, Esteban M, Adjuvant-like effect of vaccinia virus 14K protein: a case study with malaria vaccine based on the circumsporozoite protein, J. Immunol. 2012 Jun;188(12):6407-17.
• 2012
  Rodríguez D, González-Aseguinolaza G, Rodríguez JR, Vijayan A, Gherardi M, Rueda P, Casal JI, Esteban M, Vaccine efficacy against malaria by the combination of porcine parvovirus-like particles and vaccinia virus vectors expressing CS of Plasmodium, PLoS ONE 2012;7(4):e34445.
• 2011
  Wiley SR, Raman VS, Desbien A, Bailor HR, Bhardwaj R, Shakri AR, Reed SG, Chitnis CE, Carter D, Targeting TLRs expands the antibody repertoire in response to a malaria vaccine, Sci Transl Med 2011 Jul;3(93):93ra69.
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Contact

Email: chetan.chitnis@pasteur.fr

Address:
25-28 Rue du Docteur Roux
75015, Paris
France

Publié le: 11 May 2015 • Modifié le: 13 Feb 2019