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2024Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids, Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (11), pp.e2316500121. ⟨10.1073/pnas.2316500121⟩.
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2023T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations, Frontiers in Immunology, 2023, 14, pp.1163466. ⟨10.3389/fimmu.2023.1163466⟩.
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2022The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration., Sci Adv 2022 Apr; 8(15): eabl5942.
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2021Cell Polarity Regulators, Multifunctional Organizers of Lymphocyte Activation and Function., Biomed J 2021 Oct; (): .
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2020Coordinating Cytoskeleton and Molecular Traffic in T Cell Migration, Activation, and Effector Functions., Front Cell Dev Biol 2020 ; 8(): 591348.
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2020Adenomatous Polyposis Coli Modulates Actin and Microtubule Cytoskeleton at the Immunological Synapse to Tune CTL Functions., Immunohorizons 2020 06; 4(6): 363-381.
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2020ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation., Cell Rep 2020 Mar; 30(10): 3434-3447.e6.
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2019Histamine releasing factor and elongation factor 1 alpha secreted via malaria parasites extracellular vesicles promote immune evasion by inhibiting specific T cell responses., Cell Microbiol 2019 Jul; 21(7): e13021.
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2018HIV-1 Nef Hijacks Lck and Rac1 Endosomal Traffic To Dually Modulate Signaling-Mediated and Actin Cytoskeleton-Mediated T Cell Functions., J. Immunol. 2018 11; 201(9): 2624-2640.
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2018Cell Biology of T Cell Receptor Expression and Regulation., Annu. Rev. Immunol. 2018 04; 36(): 103-125.
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2017Adenomatous Polyposis Coli Defines Treg Differentiation and Anti-inflammatory Function through Microtubule-Mediated NFAT Localization., Cell Rep 2017 Oct; 21(1): 181-194.
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2017Rab11-FIP3 Regulation of Lck Endosomal Traffic Controls TCR Signal Transduction., J. Immunol. 2017 04; 198(7): 2967-2978.
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2017Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function., PLoS ONE 2017 ; 12(1): e0170396.
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2016Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation., EMBO J. 2016 06; 35(11): 1160-74.
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2016Comparative Anatomy of Phagocytic and Immunological Synapses., Front Immunol 2016 ; 7(): 18.
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2016Editorial: Molecular Dynamics at the Immunological Synapse., Front Immunol 2016 ; 7(): 632.
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2011Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation., J. Cell Biol. 2011 Nov; 195(5): 839-53.
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2011Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression., Proc. Natl. Acad. Sci. U.S.A. 2011 Aug; 108(31): 12833-8.
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2011The Shigella flexneri type three secretion system effector IpgD inhibits T cell migration by manipulating host phosphoinositide metabolism., Cell Host Microbe 2011 Apr; 9(4): 263-72.
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2010Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse., EMBO J. 2010 Jul; 29(14): 2301-14.
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2009Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events., J. Immunol. 2010 Feb; 184(3): 1436-44.
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2008Tailoring T-cell receptor signals by proximal negative feedback mechanisms., Nat Rev Immunol 2008 Sep; 8(9): 699-712.
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2007A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76., J Exp Med 2007 Mar; 204(3): 681-91.
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2007ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation., EMBO J. 2007 Jan; 26(2): 516-26.
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2005CD8 T cell sensory adaptation dependent on TCR avidity for self-antigens., J. Immunol. 2005 Dec; 175(11): 7388-97.
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2005Sequence tag scanning: a new explorative strategy for recognition of unexpected protein alterations by nanoelectrospray ionization-tandem mass spectrometry, Proteomics 2005 Feb;5(3):667-74.
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2004Large-scale screening for genes involved in T-cell signaling: do we know all the players now?, Trends Immunol. 2004 Aug; 25(8): 399-402.
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2004T-cell receptor-induced phosphorylation of the zeta chain is efficiently promoted by ZAP-70 but not Syk, Blood 2004 Aug;104(3):760-7.
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2003Proximal changes in signal transduction that modify CD8+ T cell responsiveness in vivo, Eur. J. Immunol. 2003 Sep;33(9):2551-6.
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2003Induction of the NF-kappaB cascade by recruitment of the scaffold molecule NEMO to the T cell receptor, Immunity 2003 Jan;18(1):13-26.
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2002In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern, Immunity 2002 Oct;17(4):389-99.
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2002TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70., J. Immunol. 2002 Aug; 169(4): 1705-12.
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2002Tyrosine 315 determines optimal recruitment of ZAP-70 to the T cell antigen receptor., Eur. J. Immunol. 2002 02; 32(2): 568-75.
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2001T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase, J. Exp. Med. 2001 Aug;194(4):491-505.
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2001Functional dichotomy in natural killer cell signaling: Vav1-dependent and -independent mechanisms, J. Exp. Med. 2001 Jun;193(12):1413-24.
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1999The Rift Valley fever virus nonstructural protein NSs is phosphorylated at serine residues located in casein kinase II consensus motifs in the carboxy-terminus., Virology 1999 Oct; 263(2): 517-25.
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1999Redundant role of the Syk protein tyrosine kinase in mouse NK cell differentiation, J. Immunol. 1999 Aug;163(4):1769-74.
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1999Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck., J. Biol. Chem. 1999 May; 274(20): 14229-37.
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1999Tyrosine 319, a newly identified phosphorylation site of ZAP-70, plays a critical role in T cell antigen receptor signaling., J Biol Chem 1999 Mar; 274(10): 6285-94.
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1998An improved retroviral gene transfer technique demonstrates inhibition of CD4-CD8- thymocyte development by kinase-inactive ZAP-70, J. Immunol. 1998 Sep;161(6):2888-94.
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1997Further evidence for an endogenous digitalis-like compound in newborn and adult plasma detected by anti-ouabain antiserum, Life Sci. 1997;60(12):893-8.
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1996Mutation of tyrosines 492/493 in the kinase domain of ZAP-70 affects multiple T-cell receptor signaling pathways., J Biol Chem 1996 Dec; 271(51): 32644-52.
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1996Binding of human GM-CSF to synthetic peptides of the alpha subunit of its receptor, J. Recept. Signal Transduct. Res. 1996 Jan-Mar;16(1-2):77-92.
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1995The stimulatory effect on human erythrocyte rubidium-86 uptake by anti-cardiac-glycoside antibodies, Q J Nucl Med 1995 Jun;39(2):134-9.
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1995Autoantibodies directed against ribosomal P proteins: use of a multiple antigen peptide as the coating agent in ELISA, J. Immunol. Methods 1995 Feb;179(2):193-202.
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1995Evidence for an endogenous ouabain-like immunoreactive factor in human newborn plasma coeluted with ouabain on HPLC, Life Sci. 1995;57(15):1417-25.
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1994An immunodominant epitope in a functional domain near the N-terminus of human granulocyte-macrophage colony-stimulating factor identified by cross-reaction of synthetic peptides with neutralizing anti-protein and anti-peptide antibodies, Hybridoma 1994 Dec;13(6):457-68.
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1993BQ-123 inhibits both endothelin 1 and endothelin 3 mediated C6 rat glioma cell proliferation suggesting an atypical endothelin receptor, J. Biol. Regul. Homeost. Agents 1993 Jul-Sep;7(3):95-8.