Depuis 2019 je suis responsable du groupe Wet-Lab au sein de la Plateforme Biomics, renforçant mes compétences en management développées pendant 15 ans au sein de la première Animalerie poisson (poisson zèbre) du campus. La microscopie confocale et un large panel de techniques de biologie moléculaire et d’immuno-chimie ont été les principaux outils pour explorer l’Immunité Innée chez le zebrafish. Avant ces aventures aquatiques, je travaillais avec des bactéries anaérobies telles que Clostridium perfringens et Bacteroides fragilis, mais c’était il y a un certain temps déjà. 
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Professional Experiences
Since 2019 Research engineer (Institut Pasteur, Paris, FR)
Wet-Lab Group Leader Biomics Platform headed by M. Monot
Since 2018 Research engineer (Institut Pasteur, Paris, FR)
Innate Immunity in zebrafish / Fish Facility Management
Macrophages and Development of Immunity headed by P. Herbomel
1994-2018 Research Technician (Institut Pasteur, Paris, FR)
Innate Immunity in zebrafish / Fish Facility creation and Management
Macrophages and Development of Immunity headed by P. Herbomel
Oxidative stress in Clostridium perfringens
Génétique Moléculaire Bactérienne headed by Pr S. T. Cole
Resistance to 5-nitroimidazole of Bacteroides fragilis
Unité des Anaérobies headed by Pr M. Sebald
1990-93 Technician (Institut Pasteur, Paris, FR)
National Reference Center Salmonella and Shigella
Unité des Entérobactéries headed by Pr P. Grimont
Education
1994 DUT Biology Université Paris XII, FR
Publications
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2021RNase R is associated in a functional complex with the RhpA DEAD-box RNA helicase in Helicobacter pylori., Nucleic Acids Res 2021 Apr; (): .
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2021Mining zebrafish microbiota reveals key community-level resistance against fish pathogen infection., ISME J 2021 Mar; 15(3): 702-719.
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2019IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity., J. Immunol. 2019 12; 203(12): 3361-3373.
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2017FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection., Front Immunol 2017 ; 8(): 617.
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2017Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes., Dis Model Mech 2017 07; 10(7): 847-857.
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2015Zebrafish Plzf transcription factors enhance early type I IFN response induced by two non-enveloped RNA viruses, Dev. Comp. Immunol. 2016 Apr;57:48-56.
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2015Characterization of samhd1 morphant zebrafish recapitulates features of the human type I interferonopathy Aicardi-Goutières syndrome., J. Immunol. 2015 Mar; 194(6): 2819-25.
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2014Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes., J. Immunol. 2014 May; 192(9): 4328-41.
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2013Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish., PLoS Pathog. 2013 ; 9(9): e1003619.
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2013Zebrafish ISG15 exerts a strong antiviral activity against RNA and DNA viruses and regulates the interferon response, J. Virol. 2013 Sep;87(18):10025-36.
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