Projets Projet En cours 10 Membres Candida albicans colonization of abiotic and biotic surfaces Christophe D’Enfert (PI) Biofilms formed by C. albicans on indwelling devices play a major role in the persistence of nosocomial infections, largely because of their elevated tolerance to antifungals. The Fungal Biology and Pathogenicity Unit at Institut […] Projet En cours 6 Membres Regulation of Candida albicans morphogenesis Christophe D’Enfert (PI) The Fungal Biology and Pathogenicity Unit at Institut Pasteur is interested in the regulation of the yeast-to-hypha transition in C. albicans because of its role in biofilm formation and, more generally, in virulence. While […] Projet En cours 5 Membres CANDIHUB Christophe D’Enfert (PI) Candida albicans and Candida glabrata are the two major yeast species responsible for invasive fungal infections in humans. Systemic infections due to C. albicans and C. glabrata are associated with high mortality rates despite […]
Publications Télécharger 2020 Hernández-Cervantes A, Znaidi S, van Wijlick L, Denega I, Basso V, Ropars J, Sertour N, Sullivan D, Moran G, Basmaciyan L, Bon F, Dalle F, Bougnoux ME, Boekhout T, Yang Y, Li Z, Bachellier-Bassi S, d'Enfert C, , A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans., Nat Commun 2020 12; 11(1): 6224. 2018 Znaidi S, van Wijlick L, Hernández-Cervantes A, Sertour N, Desseyn JL, Vincent F, Atanassova R, Gouyer V, Munro CA, Bachellier-Bassi S, Dalle F, Jouault T, Bougnoux ME, d'Enfert C, Systematic gene overexpression in Candida albicans identifies a regulator of early adaptation to the mammalian gut, Cell. Microbiol. 2018 Jul;:e12890.