Alexandre Alanio

Histoplasmosis is an endemic mycosis caused by the dimorphic fungus Histoplasma capsulatum. It is found as a mold in the environment and as a yeast at body temperature during infection. This organism is endemic […]

The pathogenic yeast Cryptococcus neoformans undergoes morphological changes in cell size during host interaction, producing a high percentage of Titan cells (> 10 μm) instead of the typical size 5 to 7 μm cells. We […]

Pneumocystis jirovecii is an atypical fungus responsible for severe life-threatening pneumonia (pneumocystosis) in immunocompromised patients such as HIV positive patients, solid organ transplant recipients, patients with solid tumors or hematological malignancy, and patients receiving […]

Cryptococcus neoformans and C. gattii are encapsulated yeasts that can cause life-threatening disease; mainly in immune-suppressed patients, but also in immune-competent individuals. Cryptococcosis affects the lung and may spread to the brain, manifesting itself […]

High Dose AMBISOME on a Fluconazole Backbone for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: A Phase 3 Randomised Controlled Non-Inferiority Trial This ongoing multi-centre clinical trial (ISRCTN72509687), sponsored by the London School of […]

 Cryptococcus neoformans is a sugar-coated yeast that is able to interact closely with numerous organisms in the environment including amebae, paramecium of nematodes. The interaction with these organisms probably shaped its virulence. The ability […]

Please note that this page is under construction This community is composed of MD and MD-PhD who are working in hospitals. They agree to help researchers from Institut Pasteur to identify clinical partners. Choose […]

Cryptococcus neoformans is a haploid yeast with a bipolar propagation system (asexual multiplication + sexual reproduction) giving rise to haploids, diploids and hybrids. It exists in two varieties neoformans (serotype D) and grubii (serotype […]

Compared with other infectious diseases, invasive mycoses are neglected diseases. They remained poorly known, underdiagnosed and understudied in many countries around the world despite the increasing public health burden they represent now. The population […]

A nationwide network of dedicated clinicians and microbiologists/mycologists composing the French Mycoses Study Group who diagnose and treat the patients with invasive fungal infections contribute to the surveillance programs by notifying their cases through […]