Medical Mycology Course in Africa
The Molecular Mycology Unit (Institut Pasteur), the AFGrica Unit (University of Aberdeen & University of Cape Town) and the AMBITION-cm Trial Consortium are pleased to announce a one-week English-speaking course for scientists and clinicians […]
Improve molecular methods to detect Histoplasma capsulatum in humans
Histoplasmosis is an endemic mycosis caused by the dimorphic fungus Histoplasma capsulatum. It is found as a mold in the environment and as a yeast at body temperature during infection. This organism is endemic […]
Understanding the genesis of the Titan cells in Cryptococcus neoformans
The pathogenic yeast Cryptococcus neoformans undergoes morphological changes in cell size during host interaction, producing a high percentage of Titan cells (> 10 μm) instead of the typical size 5 to 7 μm cells. We […]
Molecular variability of Pneumocystis jirovecii: from genotype to antigenic variability
Pneumocystis jirovecii is an atypical fungus responsible for severe life-threatening pneumonia (pneumocystosis) in immunocompromised patients such as HIV positive patients, solid organ transplant recipients, patients with solid tumors or hematological malignancy, and patients receiving […]
CryptoVIEW: Unraveling pathogenesis of Cryptococcosis using optical and multimodal visualizaion of enigmatic events and virulence aspects in vivo.
Cryptococcus neoformans and C. gattii are encapsulated yeasts that can cause life-threatening disease; mainly in immune-suppressed patients, but also in immune-competent individuals. Cryptococcosis affects the lung and may spread to the brain, manifesting itself […]
High Dose AMBISOME on a Fluconazole Backbone for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: A Phase 3 Randomised Controlled Non-Inferiority Trial This ongoing multi-centre clinical trial (ISRCTN72509687), sponsored by the London School of […]
Deciphering dormancy in Cryptocococcus neoformans
Cryptococcus neoformans is a sugar-coated yeast that is able to interact closely with numerous organisms in the environment including amebae, paramecium of nematodes. The interaction with these organisms probably shaped its virulence. The ability […]
Communauté des médecins affiliés de l’Institut Pasteur
Please note that this page is under construction This community is composed of MD and MD-PhD who are working in hospitals. They agree to help researchers from Institut Pasteur to identify clinical partners. Choose […]
Private: Cryptococcus neoformans diversity during infection in France
Cryptococcus neoformans is a haploid yeast with a bipolar propagation system (asexual multiplication + sexual reproduction) giving rise to haploids, diploids and hybrids. It exists in two varieties neoformans (serotype D) and grubii (serotype […]
Epidemiological studies on invasive fungal infections
Compared with other infectious diseases, invasive mycoses are neglected diseases. They remained poorly known, underdiagnosed and understudied in many countries around the world despite the increasing public health burden they represent now. The population […]
Databases on the epidemiology of invasive fungal infections in France
A nationwide network of dedicated clinicians and microbiologists/mycologists composing the French Mycoses Study Group who diagnose and treat the patients with invasive fungal infections contribute to the surveillance programs by notifying their cases through […]
2019Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype, PLoS Pathog. 2019 Jul;15(7):e1007945.
2019Correction to: AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial, Trials 2019 01;20(1):48.
2018Outcome and potentially modifiable risk factors for candidemia in critically ill burns patients: A matched cohort study, Mycoses 2019 Mar;62(3):237-246.
2018AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial, Trials 2018 Nov;19(1):649.
2018Primary antifungal prophylaxis with micafungin after allogeneic hematopoietic stem cell transplantation: a monocentric prospective study, Ann. Hematol. 2019 Apr;98(4):1033-1035.
2018Recent advances in the understanding and management of mucormycosis, F1000Res 2018;7.
2018Global guidelines and initiatives from the European Confederation of Medical Mycology to improve patient care and research worldwide: New leadership is about working together, Mycoses 2018 Nov;61(11):885-894.
2018Failure of voriconazole therapy due to acquired azole resistance in Aspergillus fumigatus in a kidney transplant recipient with chronic necrotizing aspergillosis, Am. J. Transplant. 2018 Sep;18(9):2352-2355.
2018Reactivation of dormant/latent fungal infection, J. Infect. 2018 Dec;77(6):463-468.
2018Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators, PLoS Pathog. 2018 05;14(5):e1006982.
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