Deconstructing the role of SUMO on chromatin in cell identity and tissue repair (ERC-2018-AdG SUMiDENTITY)
The maintenance of cell identity and how it is subverted in disease are central questions in biology and medicine. The interplay between transcription factor and chromatin configurations plays a key role in maintaining cellular […]
2020SUMOylation of Enzymes and Ion Channels in Sensory Neurons Protects against Metabolic Dysfunction, Neuropathy, and Sensory Loss in Diabetes., Neuron 2020 09; 107(6): 1141-1159.e7.
2020An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency., Oncogene 2020 Sep; (): .
2020Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells., Cell Rep 2020 09; 32(11): 108146.
2018SUMO safeguards somatic and pluripotent cell identities by enforcing distinct chromatin states, Cell Stem Cell. 2018 Nov 1;23(5):742-757.e8. doi: 10.1016/j.stem.2018.10.001.
2017entry unveils a calcium/calpain-dependent mechanism for inhibiting sumoylation, Elife 2017 12;6.