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Deconstructing the role of SUMO on chromatin in cell identity and tissue repair (ERC-2018-AdG SUMiDENTITY)
Anne Dejean (PI)
The maintenance of cell identity and how it is subverted in disease are central questions in biology and medicine. The interplay between transcription factor and chromatin configurations plays a key role in maintaining cellular […]
2020An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency., Oncogene 2020 Sep; (): .
2020Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells., Cell Rep 2020 Sep; 32(11): 108146.
2018SUMO safeguards somatic and pluripotent cell identities by enforcing distinct chromatin states, Cell Stem Cell. 2018 Nov 1;23(5):742-757.e8. doi: 10.1016/j.stem.2018.10.001.
2017entry unveils a calcium/calpain-dependent mechanism for inhibiting sumoylation, Elife 2017 12;6.