Présentation
The Spirochase website is an easy-to-navigate portal to all reference proteomes within the Spirochaetes phylum.
Here, proteins are organized into orthologous groups (OGs), each with a unique identifier and annotation. With Spirochase, you can easily find answers to questions like: Is my protein found in spirochetes? Is it ancestral to the entire phylum? How is it distributed across the phylogeny?
You can also explore the data directly on the Data page or dive into the latest phylogeny of Spirochaetota on the Tree page. Learn more about what an OG is in omabrowser
For details on how the data was generated, refer to the study by Huete SG et al. 2025, available here (PrePrint) .
Possible actions :
- Perform a BLAST search for your protein of interest against the reference proteomes of Spirochaetes . This will allow you to identify the OG number of your protein and find its distribution in the phylum.
- Find out the latest updated phylogeny of the phylum Spirochaetes and explore its main genera: Leptospira spp., Borrelia spp., Treponema spp., etc.
- Explore the latest annotations of the reference proteomes in the Spirochaetes phylum, selecting your groups of interest and the main functions as COG categories.
