Timeline

Lucy Glover
Head of Structure
05 Sep 2023
event

DPT Parasites and Insects Vectors Seminar Thomas OTTO“Bioinformatics tools to explore host-parasite interactions”

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07 Mar 2023
event

DPT Parasites and Insects Vectors Seminar – Virginia HOWICK “Understanding adaptation of P. falciparum to diverse Anopheles vectors”

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01 Nov 2022
publication

SHERLOCK4HAT: A CRISPR-based tool kit for diagnosis of Human African Trypanosomiasis.

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07 Sep 2022
event

Symposium “Future in Parasitology 2022”

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01 Jan 2022
publication

VEX1 Influences mVSG Expression During the Transition to Mammalian Infectivity in Trypanosoma brucei.

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12 Nov 2021
publication

DNA double strand break position leads to distinct gene expression changes and regulates VSG switching pathway choice.

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18 Aug 2021
project

SherPa

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05 Mar 2021
event

PhD defence:”DNA damage and antigenic variation in Trypanosoma brucei”-Emilia Maclaughin

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15 Jan 2021
publication

The MRN complex promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes.

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14 Aug 2019
event

Immune-mediated control of Toxoplasma in human cells – Eva Frickel

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09 Aug 2019
project

SHERLOCK4HAT

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25 Jun 2019
publication

Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex

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18 Jun 2019
publication

Persistent DNA damage foci and DNA replication with a broken chromosome in the African trypanosome

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29 May 2019
publication

A post-transcriptional respiratome regulon in trypanosomes

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18 Apr 2019
publication

CRISPR in Parasitology: Not Exactly Cut and Dried!

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26 Nov 2018
publication

Insights into antitrypanosomal drug mode-of-action from cytology-based profiling

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24 Aug 2018
event

CRISPR in Parasitology Symposium

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27 Jul 2016
publication

The nuclear envelope and gene organization in parasitic protozoa: Specializations associated with disease

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25 May 2016
publication

VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes

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01 Feb 2016
team

Trypanosome Molecular Biology

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11 Dec 2014
publication

Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes

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09 Oct 2014
publication

Locus-specific control of DNA resection and suppression of subtelomeric VSG recombination by HAT3 in the African trypanosome

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15 Sep 2014
department

Parasites and Insect Vectors

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10 Oct 2013
publication

Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control

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28 Mar 2013
publication

DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes

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18 Jun 2012
publication

Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes

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25 Jan 2012
publication

High-throughput decoding of antitrypanosomal drug efficacy and resistance

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01 Mar 2011
publication

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

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21 Oct 2010
publication

Microhomology-mediated deletion and gene conversion in African trypanosomes

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01 Aug 2009
publication

Site-specific DNA double-strand breaks greatly increase stable transformation efficiency in Trypanosoma brucei

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11 Mar 2008
publication

Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes

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