Timeline

Giulia Manina

Head of Structure

16 May 2024

publication

Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy.

16 May 2024

publication

Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy

15 Nov 2022

publication

Microfluidic dose-response platform to track the dynamics of drug response in single mycobacterial cells

20 May 2022

publication

RNase E and HupB dynamics foster mycobacterial cell homeostasis and fitness.

05 Oct 2021

publication

Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner.

01 Jan 2021

publication

Single-Cell Analysis of Mycobacteria Using Microfluidics and Time-Lapse Microscopy.

13 Nov 2020

publication

6,11-Dioxobenzo[f]pyrido[1,2-a]indoles Kill Mycobacterium tuberculosis by Targeting Iron-Sulfur Protein Rv0338c (IspQ), A Putative Redox Sensor.

11 Feb 2020

event

EMBO Workshop on Tuberculosis 2020 postponed to September 2022

01 Jan 2020

publication

Delving Into the Functional Meaning of Phenotypic Variation in Mycobacterial Persistence: Who Benefits the Most From Programmed Death of Individual Cells?

01 Jan 2020

publication

Chemical, Metabolic, and Cellular Characterization of a FtsZ Inhibitor Effective Against Burkholderia cenocepacia.

04 Oct 2019

publication

Preexisting variation in DNA damage response predicts the fate of single mycobacteria under stress

09 Mar 2017

event

Microfluidics Club at Pasteur Third Seminar: Dr. Gilgueng HWANG

22 Nov 2016

event

Cell Biology and Infection Day – December 1, 2016 Institut Pasteur, Paris, France Amphithéâtre Duclaux

11 Nov 2016

publication

Phenotypic Heterogeneity in Mycobacterium tuberculosis

21 Oct 2016

event

Microfluidic Large-Scale Integration Applied to Molecular Diagnostics. Prof. Sebastian MAERKL (EPFL)

02 Dec 2015

event

EMBO Conference Tuberculosis 2016

27 Oct 2015

project

Microfluidics@Pasteur

07 Sep 2015

project

Impact of the host on microbial individuality

07 Sep 2015

project

DNA damage response

07 Sep 2015

project

Molecular markers for cell quiescence

07 Sep 2015

project

Single-cell gene expression dynamics

11 May 2015

team

Microbial Individuality and Infection

01 Jan 2015

publication

Single-cell analysis of mycobacteria using microfluidics and time-lapse microscopy

24 Dec 2014

publication

Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms

14 Sep 2013

publication

The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis

01 Jan 2013

publication

A single-cell perspective on non-growing but metabolically active (NGMA) bacteria

01 Jan 2010

publication

Decaprenylphosphoryl-β-D-ribose 2′-epimerase from Mycobacterium tuberculosis is a magic drug target

19 Mar 2009

publication

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

11 Oct 2008

publication

Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system

16 Oct 2006

publication

LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis

20 Jul 2006

publication

A little guide for advanced search:

Timeline

Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy.

Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy

Microfluidic dose-response platform to track the dynamics of drug response in single mycobacterial cells

RNase E and HupB dynamics foster mycobacterial cell homeostasis and fitness.

Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner.

Single-Cell Analysis of Mycobacteria Using Microfluidics and Time-Lapse Microscopy.

6,11-Dioxobenzo[f]pyrido[1,2-a]indoles Kill Mycobacterium tuberculosis by Targeting Iron-Sulfur Protein Rv0338c (IspQ), A Putative Redox Sensor.

EMBO Workshop on Tuberculosis 2020 postponed to September 2022

Delving Into the Functional Meaning of Phenotypic Variation in Mycobacterial Persistence: Who Benefits the Most From Programmed Death of Individual Cells?

Chemical, Metabolic, and Cellular Characterization of a FtsZ Inhibitor Effective Against Burkholderia cenocepacia.

Preexisting variation in DNA damage response predicts the fate of single mycobacteria under stress

Microfluidics Club at Pasteur Third Seminar: Dr. Gilgueng HWANG

Cell Biology and Infection Day – December 1, 2016 Institut Pasteur, Paris, France Amphithéâtre Duclaux

Phenotypic Heterogeneity in Mycobacterium tuberculosis

Microfluidic Large-Scale Integration Applied to Molecular Diagnostics. Prof. Sebastian MAERKL (EPFL)

EMBO Conference Tuberculosis 2016

Microfluidics@Pasteur

Impact of the host on microbial individuality

DNA damage response

Molecular markers for cell quiescence

Single-cell gene expression dynamics

Microbial Individuality and Infection

Single-cell analysis of mycobacteria using microfluidics and time-lapse microscopy

Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms

The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis

A single-cell perspective on non-growing but metabolically active (NGMA) bacteria

Decaprenylphosphoryl-β-D-ribose 2′-epimerase from Mycobacterium tuberculosis is a magic drug target

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system

LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis

Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome