Timeline

Sophie Vichier-Guerre
Permanent Researcher
22 Feb 2020
publication

Fermentation Products of Commensal Bacteria Alter Enterocyte Lipid Metabolism

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20 Jun 2019
publication

Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4

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02 Feb 2019
publication

First-in-class allosteric inhibitors of bacterial IMPDHs

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02 Jan 2019
team

Organic Chemistry

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02 Jan 2019
publication

2′-Deoxyribonucleoside 5′-triphosphates bearing 4-phenyl and 4-pyrimidinyl imidazoles as DNA polymerase substrates

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09 Mar 2018
project

Protein synthesis machinery of Trypanosomatid as a therapeutic target

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12 Sep 2017
publication

An expedient synthesis of flexible nucleosides via a regiocontrolled enzymatic glycosylation of functionalized imidazoles

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18 Nov 2016
team

Group : Sylvie Pochet

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11 Mar 2016
publication

Expedient and generic synthesis of imidazole nucleosides by enzymatic transglycosylation

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03 Sep 2015
project

Inhibitors of Pseudomonas aeruginosa IMPDH

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11 May 2015
team

Chemistry and Biocatalysis

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12 Nov 2014
publication

A convenient synthesis of 4(5)-(hetero)aryl-1H-imidazoles via microwave-assisted Suzuki-Miyaura cross-coupling reaction

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01 Sep 2010
publication

Characterisation of a DNA polymerase highly mutated along the template binding interface

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18 Aug 2010
publication

Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant

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01 Dec 2006
publication

Carbohydrate antigens: synthesis aspects and immunological applications in cancer

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18 Sep 2006
publication

A population of thermostable reverse transcriptases evolved from Thermus aquaticus DNA polymerase I by phage display

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18 Oct 2005
publication

How to broaden enzyme substrate specificity: strategies, implications and applications

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15 Jul 2004
publication

A fully synthetic therapeutic vaccine candidate targeting carcinoma-associated Tn carbohydrate antigen induces tumor-specific antibodies in nonhuman primates

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01 Jul 2004
publication

Synthesis and immunological evaluation of an antitumor neoglycopeptide vaccine bearing a novel homoserine Tn antigen

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01 Sep 2003
publication

Induction of carbohydrate-specific antibodies in HLA-DR transgenic mice by a synthetic glycopeptide: a potential anti cancer vaccine for human use

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14 Apr 2003
publication

Iterative cycles of in vitro protein selection for DNA polymerase activity

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15 Feb 2001
publication

Anti-tumor immunity provided by a synthetic multiple antigenic glycopeptide displaying a tri-Tn glycotope

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01 Feb 2001
publication

High density O-glycosylation of the MUC2 tandem repeat unit by N-acetylgalactosaminyltransferase-3 in colonic adenocarcinoma extracts

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01 Feb 2000
publication

Short synthetic glycopeptides successfully induce antibody responses to carcinoma-associated Tn antigen

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01 Apr 1999
publication

A fully synthetic immunogen carrying a carcinoma-associated carbohydrate for active specific immunotherapy

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09 Jul 1998
publication

Selective mRNA degradation by antisense oligonucleotide-2,5A chimeras: Involvement of RNase H and RNase L

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04 Apr 1997
publication

Stereoisomers of Deoxynucleoside 5′-Triphosphates as Substrates for Template-dependent and -independent DNA Polymerases

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01 Jan 1994
publication

New Insights into the Resistance of α-Oligonucleotides to Nucleases

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