Ligne de temps

Sophie Vichier-Guerre
Chercheur(euse) Permanent(e)
16 mai 2024
publication

Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy

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16 mai 2024
publication

Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy

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18 avr. 2024
publication

Adenine, a key player in biology and medicinal chemistry 

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07 févr. 2023
publication

Interaction network among de novo purine nucleotide biosynthesis enzymes in Escherichia coli.

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01 juin 2022
publication

Identification of Chemical Probes Targeting MBD2.

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22 févr. 2020
publication

Fermentation Products of Commensal Bacteria Alter Enterocyte Lipid Metabolism

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03 janv. 2020
publication

An expedient synthesis of flexible nucleosides through enzymatic glycosylation of proximal and distal fleximer bases

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20 juin 2019
publication

Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4

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02 févr. 2019
publication

First-in-class allosteric inhibitors of bacterial IMPDHs

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02 janv. 2019
publication

2′-Deoxyribonucleoside 5′-triphosphates bearing 4-phenyl and 4-pyrimidinyl imidazoles as DNA polymerase substrates

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09 mars 2018
project

Protein synthesis machinery of Trypanosomatid as a therapeutic target

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09 janv. 2018
team

Chimie Biologique Epigénétique

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12 sept. 2017
publication

An expedient synthesis of flexible nucleosides via a regiocontrolled enzymatic glycosylation of functionalized imidazoles

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11 mars 2016
publication

Expedient and generic synthesis of imidazole nucleosides by enzymatic transglycosylation

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03 sept. 2015
project

Inhibitors of Pseudomonas aeruginosa IMPDH

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12 nov. 2014
publication

A convenient synthesis of 4(5)-(hetero)aryl-1H-imidazoles via microwave-assisted Suzuki-Miyaura cross-coupling reaction

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01 sept. 2010
publication

Characterisation of a DNA polymerase highly mutated along the template binding interface

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18 août 2010
publication

Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant

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01 déc. 2006
publication

Carbohydrate antigens: synthesis aspects and immunological applications in cancer

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18 sept. 2006
publication

A population of thermostable reverse transcriptases evolved from Thermus aquaticus DNA polymerase I by phage display

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18 oct. 2005
publication

How to broaden enzyme substrate specificity: strategies, implications and applications

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01 juil. 2004
publication

Synthesis and immunological evaluation of an antitumor neoglycopeptide vaccine bearing a novel homoserine Tn antigen

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01 sept. 2003
publication

Induction of carbohydrate-specific antibodies in HLA-DR transgenic mice by a synthetic glycopeptide: a potential anti cancer vaccine for human use

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14 avr. 2003
publication

Iterative cycles of in vitro protein selection for DNA polymerase activity

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15 févr. 2001
publication

Anti-tumor immunity provided by a synthetic multiple antigenic glycopeptide displaying a tri-Tn glycotope

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01 févr. 2001
publication

High density O-glycosylation of the MUC2 tandem repeat unit by N-acetylgalactosaminyltransferase-3 in colonic adenocarcinoma extracts

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01 févr. 2000
publication

Short synthetic glycopeptides successfully induce antibody responses to carcinoma-associated Tn antigen

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01 avr. 1999
publication

A fully synthetic immunogen carrying a carcinoma-associated carbohydrate for active specific immunotherapy

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09 juil. 1998
publication

Selective mRNA degradation by antisense oligonucleotide-2,5A chimeras: Involvement of RNase H and RNase L

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04 avr. 1997
publication

Stereoisomers of Deoxynucleoside 5′-Triphosphates as Substrates for Template-dependent and -independent DNA Polymerases

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01 janv. 1994
publication

New Insights into the Resistance of α-Oligonucleotides to Nucleases

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