Timeline

Nazarii Sabat

Permanent Researcher

10 Feb 2025

event

HALF-DAY DRUG DISCOVERY, Department of Structural Biology and Chemistry

24 Jan 2025

publication

Recent Advances in Biocatalytic and Chemoenzymatic Synthesis of Oligonucleotides

13 Sep 2024

publication

Template-dependent DNA ligation for the synthesis of modified oligonucleotides.

13 Sep 2024

publication

Template-dependent DNA ligation for the synthesis of modified oligonucleotides.

15 Nov 2023

publication

Artificial nucleotide codons for enzymatic DNA synthesis

01 Jan 2023

publication

Towards the controlled enzymatic synthesis of LNA containing oligonucleotides.

26 Aug 2022

publication

Benzoyl and pivaloyl as efficient protecting groups for controlled enzymatic synthesis of DNA and XNA oligonucleotides

16 May 2022

publication

Unbiased C3-Electrophilic Indoles: Triflic Acid Mediated C3-Regioselective Hydroarylation of N-H Indoles

16 Mar 2022

publication

Enantioselective Au(I)-Catalyzed Multicomponent Annulation via Tethered Counterion-Directed Catalysis

10 Mar 2022

publication

Synthesis, antiviral and antitumor activities investigations of a series of Ribavirin C-nucleoside analogue prodrugs

07 Mar 2022

publication

Biochemical and XAS investigation of TsrM, a B12-dependent Radical SAM Enzyme Catalyzing Non-radical reaction

14 Jul 2020

publication

Gold-Catalyzed Enantioselective Functionalizations of Indoles

12 May 2020

publication

Gold-Catalyzed Spirocyclization Reactions of N-propargyl Tryptamines and Tryptophanes in Aqueous Media

21 Dec 2019

publication

Synthesis and antitumor activities investigation of a C-nucleoside analogue of ribavirin

30 Apr 2018

publication

C-H Imidation of 7-Deazapurines.

01 Oct 2017

publication

Synthesis of 2,6-Substituted-7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted-5-(Het)aryl-pyrrolo[2,3-d]pyrimidines

01 Nov 2016

publication

Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions

07 Oct 2016

publication

C-H Phosphonation of Pyrrolopyrimidines: Synthesis of Substituted 7- and 9-Deazapurine-8-phosphonate Derivatives.

12 Jan 2016

team

Bioorganic chemistry of nucleic acids

27 Oct 2015

publication

Ir-catalyzed C–H silylations of phenyldeazapurines.

25 Oct 2014

publication

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Timeline

HALF-DAY DRUG DISCOVERY, Department of Structural Biology and Chemistry

Recent Advances in Biocatalytic and Chemoenzymatic Synthesis of Oligonucleotides

Template-dependent DNA ligation for the synthesis of modified oligonucleotides.

Template-dependent DNA ligation for the synthesis of modified oligonucleotides.

Artificial nucleotide codons for enzymatic DNA synthesis

Towards the controlled enzymatic synthesis of LNA containing oligonucleotides.

Benzoyl and pivaloyl as efficient protecting groups for controlled enzymatic synthesis of DNA and XNA oligonucleotides

Unbiased C3-Electrophilic Indoles: Triflic Acid Mediated C3-Regioselective Hydroarylation of N-H Indoles

Enantioselective Au(I)-Catalyzed Multicomponent Annulation via Tethered Counterion-Directed Catalysis

Synthesis, antiviral and antitumor activities investigations of a series of Ribavirin C-nucleoside analogue prodrugs

Biochemical and XAS investigation of TsrM, a B12-dependent Radical SAM Enzyme Catalyzing Non-radical reaction

Gold-Catalyzed Enantioselective Functionalizations of Indoles

Gold-Catalyzed Spirocyclization Reactions of N-propargyl Tryptamines and Tryptophanes in Aqueous Media

Synthesis and antitumor activities investigation of a C-nucleoside analogue of ribavirin

C-H Imidation of 7-Deazapurines.

Synthesis of 2,6-Substituted-7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted-5-(Het)aryl-pyrrolo[2,3-d]pyrimidines

Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions

C-H Phosphonation of Pyrrolopyrimidines: Synthesis of Substituted 7- and 9-Deazapurine-8-phosphonate Derivatives.

Bioorganic chemistry of nucleic acids

Ir-catalyzed C–H silylations of phenyldeazapurines.

Direct C–H amination and C–H chloroamination of 7-deazapurines.