Timeline

Mathilde Dusseaux

Head of Facility

23 May 2025

publication

Intra-tumoral delivery of FLT3L with CXCR3/CCR5 ligands promotes XCR1+ DC1 infiltration and activates anti-tumor immunity

01 Apr 2024

publication

Anti-PD-1 therapy triggers Tfh cell-dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes.

25 Mar 2024

news

New publication – Anti-PD-1 therapy triggers Tfh cell–dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes

18 Jul 2022

publication

Preclinical Development and Evaluation of Allogeneic CAR T Cells Targeting CD70 for the Treatment of Renal Cell Carcinoma.

30 Jun 2022

publication

Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing.

08 Nov 2021

team

Human Disease Models core facility

01 Jun 2019

publication

Accelerated thymopoiesis and improved T-cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice.

01 Aug 2018

publication

A human immune system mouse model with robust lymph node development.

26 Aug 2017

publication

Viral Load Affects the Immune Response to HBV in Mice With Humanized Immune System and Liver.

06 Apr 2017

publication

A functional DC cross talk promotes human ILC homeostasis in humanized mice.

17 Mar 2015

publication

A novel mouse model for stable engraftment of a human immune system and human hepatocytes.

01 Jan 2014

publication

Animal models to test hiPS-derived hepatocytes in the context of inherited metabolic liver diseases.

01 Jan 2013

publication

MAIT cells detect and efficiently lyse bacterially-infected epithelial cells.

01 May 2011

publication

Mucosal-associated invariant T cells: unconventional development and function.

01 Feb 2011

publication

A new Ser472Asn (Cab2(a+)) polymorphism localized within the αIIb “thigh” domain is involved in neonatal thrombocytopenia.

27 Jan 2011

publication

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells.

01 Aug 2010

publication

Antimicrobial activity of mucosal-associated invariant T cells.

15 Jul 2010

publication

Long peptide vaccination can lead to lethality through CD4+ T cell-mediated cytokine storm.

01 Mar 2010

publication

AlphaIIbbeta3 integrin: new allelic variants in Glanzmann thrombasthenia, effects on ITGA2B and ITGB3 mRNA splicing, expression, and structure-function.

A little guide for advanced search:

Intra-tumoral delivery of FLT3L with CXCR3/CCR5 ligands promotes XCR1+ DC1 infiltration and activates anti-tumor immunity

Anti-PD-1 therapy triggers Tfh cell-dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes.

New publication – Anti-PD-1 therapy triggers Tfh cell–dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes

Preclinical Development and Evaluation of Allogeneic CAR T Cells Targeting CD70 for the Treatment of Renal Cell Carcinoma.

Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing.

Human Disease Models core facility

Accelerated thymopoiesis and improved T-cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice.

A human immune system mouse model with robust lymph node development.

Viral Load Affects the Immune Response to HBV in Mice With Humanized Immune System and Liver.

A functional DC cross talk promotes human ILC homeostasis in humanized mice.

A novel mouse model for stable engraftment of a human immune system and human hepatocytes.

Animal models to test hiPS-derived hepatocytes in the context of inherited metabolic liver diseases.

MAIT cells detect and efficiently lyse bacterially-infected epithelial cells.

Mucosal-associated invariant T cells: unconventional development and function.

A new Ser472Asn (Cab2(a+)) polymorphism localized within the αIIb “thigh” domain is involved in neonatal thrombocytopenia.

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells.

Antimicrobial activity of mucosal-associated invariant T cells.

Long peptide vaccination can lead to lethality through CD4+ T cell-mediated cytokine storm.

AlphaIIbbeta3 integrin: new allelic variants in Glanzmann thrombasthenia, effects on ITGA2B and ITGB3 mRNA splicing, expression, and structure-function.