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  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
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Scientific Fields
Diseases
Organisms
Applications
Technique

Former Members

2000
2000
Name
Position
2014
2016
Isidro Cortes Ciriano
PhD Student
2018
2020
Irène Pitard
PhD Student
2017
2018
Bradley Worley
postdoctoral researcher
2021
2021
Georg Daniel Förster
postdoctoral researcher

Projects

Project
Ongoing
3 Members

Conformational sampling and functional dynamics of histidine kinases

Nathalie Duclert-Savatier (PI)

Two-component systems (TCS) play an important role as to allow organisms to sense and respond to changes in many different environmental conditions. Histidine kinases are one component of many TCS, and are able to […]
Project
Ongoing
2 Members

Development of inhibitors targeting the allosteric activation of adenyl cyclases

Thérèse Malliavin (PI)

We propose to develop a new strategy to inhibit bacterial adenyl cyclase toxins essential to the pathogenicity of several bacteria, by specifically targeting their allosteric activation. For this purpose, the analysis of the family […]
Project
Ongoing
3 Members

Computational geometry for the determination of biomolecular structures

Thérèse Malliavin (PI)

During the last decades, structural biology allowed to incredibly improve the information on the biological objects, from single biomolecules to molecular assemblies, and to get a better description  of the physics underlying the interactions […]
Project
Ongoing
26 Members

CyaA secretion, folding and translocation across membrane

Alexandre Chenal (PI)

CyaA, a 1706 residue-long protein, is one of the major virulence factors produced by B. pertussis and plays an important role in the early stages of respiratory tract colonization. This toxin uses an original […]

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Contact

Phone: Email: therese.malliavin@pasteur.fr Address 25-28 Rue du Docteur Roux 75015, Paris France