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  • tool
  • patent
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  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
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  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
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  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Structure
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© Research
Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
15
Nov 2016
Status
Ongoing
Members
1
Structures
1

About

Negative stain and Cryo-electron microscopy is used to provide structural information of macromolecules and their complexes by imaging non-crystalline speciments (single particles) absorbed in electron microscopy grids.

Access Protocol

  1. Project requests should be submitted through the online PPMS system.
  2. Shortly after, you will be invited to briefly introduce your project in one of Ultrapole meetings and discuss how to best address your questions. During this meeting be prepared to provide information on sample purification protocol and on its composition and heterogenity (Size Exclusion Chromatography or other methods). Mass Spectrometry, UV singnature and Dynamic Light Scattering services can be provided by the Center of Biophysics of Macromolecules and their Interactions (PFBMI facility) of Institute Pasteur as an Initial Assesment package for your sample.
  3. You will be asked to provide an inactivation protocol in case your project deals with pathogens of P2/P3 bio-safety level before bringing your samples to our facility.