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Appointments

Deputy Director of Center
Deputy Director of Department
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Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

Content 2

Content Type

member
team
department
center
program_project
nrc
whocc
project
software
tool
patent

Keywords

Positions

Administrative Staff
Assistant Professor
Associate Professor
Clinical Research Assistant
Clinical Research Nurse
Clinician Researcher
Department Manager
Dual-education Student
Full Professor
Honorary Professor
Lab assistant
Master Student
Non-permanent Researcher
Nursing Staff
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
Prize
Project Manager
Research Associate
Research Engineer
Retired scientist
Technician
Undergraduate Student
Veterinary
Visiting Scientist

Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

2018

Publication

CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair.

Nature Communications

Charpentier M, Khedher AHY, Menoret S, Brion A, Lamribet K, Dardillac E, Boix C, Perrouault L, Tesson L, Geny S, De Cian A, Itier JM, Anegon I, Lopez B, Giovannangeli C and Concordet JP

2017

Publication

Lack of interaction between NEMO and SHARPIN impairs linear ubiquitination and NF-κB activation and leads to incontinentia pigmenti.

Journal of Allergy and Clinical Immunology

Bal E, Laplantine E, Hamel Y, Dubosclard V, Boisson B, Pescatore A, Picard C, Hadj-Rabia S, Royer G, Steffann J, Bonnefont JP, Ursini VM, Vabres P, Munnich A, Casanova JL, Bodemer C, Weil R, Agou F, Smahi A

2016

Publication

HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell

PLoS Pathogens

Boullé M, Müller TG, Dähling S, Ganga Y, Jackson L, Mahamed D, Oom L, Lustig G, Neher RA, Sigal A

2021

Publication

Interrogating RNA and protein spatial subcellular distribution in smFISH data with DypFISH

Cell Reports Methods

Anca F. Savulescu, Robyn Brackin, Emmanuel Bouilhol, Benjamin Dartigues, Jonathan H. Warrell, Mafalda R. Pimentel, Nicolas Beaume, Isabela C. Fortunato, Stephane Dallongeville, Mikaël Boullé, Hayssam Soueidan, Fabrice Agou, Jan Schmoranzer, Jean-Christophe Olivo-Marin, Claudio A. Franco, Edgar R. Gomes, Macha Nikolski, and Musa M. Mhlanga

2023

Publication

Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMPDHs.

Protein science : a publication of the Protein Society

Gedeon A, Ayoub N, Brûlé S, Raynal B, Karimova G, Gelin M, Mechaly A, Haouz A, Labesse G, Munier-Lehmann H

2021

Publication

A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy

ChemRxiv

Luke K. McKenzie, Marie Flamme, Patrick S. Felder, Johannes Karges, Frederic Bonhomme, Albert Gandioso, Christian Malosse, Gilles Gasser*, Marcel Hollenstein*

2022

Publication

A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors.

Antiviral research

Chen KY, Krischuns T, Varga LO, Harigua-Souiai E, Paisant S, Zettor A, Chiaravalli J, Delpal A, Courtney D, O'Brien A, Baker SC, Decroly E, Isel C, Agou F, Jacob Y, Blondel A, Naffakh N,

2015

Publication

Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation

Acta crystallographica. Section D, Biological crystallography

Labesse G, Alexandre T, Gelin M, Haouz A, Munier-Lehmann H

2023

Publication

Interaction network among de novo purine nucleotide biosynthesis enzymes in Escherichia coli.

The FEBS journal

Gedeon A, Karimova G, Ayoub N, Dairou J, Giai Gianetto Q, Vichier-Guerre S, Vidalain PO, Ladant D, Munier-Lehmann H

2016

Publication

Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions

Synthesis

Sabat, N.; Nauš, P.; Matyašovský, J.; Dziuba, D.; Poštová Slavetínská, L.; Hocek, M.

2021

Publication

Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA.

Nature communications

Czernecki D, Bonhomme F, Kaminski PA, Delarue M

2020

Publication

The fully synthetic glycopeptide MAG-Tn3 therapeutic vaccine induces tumor-specific cytotoxic antibodies in breast cancer patients.

Cancer immunology, immunotherapy : CII

Rosenbaum P, Artaud C, Bay S, Ganneau C, Campone M, Delaloge S, Gourmelon C, Loirat D, Medioni J, Pein F, Sablin MP, Tredan O, Varga A, Leclerc C,

2017

Publication

Synthesis of 2,6-Substituted-7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted-5-(Het)aryl-pyrrolo[2,3-d]pyrimidines

Synthesis

Sabat, N.; Smolén. S.; Nauš, P.; Perlíková. P.; Cebová. M.; Poštová Slavětínská, L.; Hocek, M.

2019

Publication

An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis

Science Translational Medicine

Friederike Jönsson*, Luc de Chaisemartin*, Vanessa Granger†, Aurélie Gouel-Chéron†, Caitlin M. Gillis, Qianqian Zhu, Fadia Dib, Pascale Nicaise-Roland, Christelle Ganneau, Maria Hurtado-Nedelec, Catherine Paugam-Burtz, Skander Necib, Hawa Keita-Meyer, Matthieu Le Dorze, Bernard Cholley, Olivier Langeron, Laurent Jacob, Benoit Plaud, Marc Fischler, Caroline Sauvan, Marie-Thérèse Guinnepain, Philippe Montravers, Michel Aubier, Sylvie Bay, Catherine Neukirch, Florence Tubach‡, Dan Longrois‡, Sylvie Chollet-Martin‡,§ and Pierre Bruhns‡,§

2021

Publication

Multigram synthesis of an orthogonally-protected pentasaccharide for use as a glycan precursor in a Shigella flexneri 3a conjugate vaccine: application to a ready-for-conjugation decasaccharide

Org. Chem. Front.

2019

Publication

Synthesis and antitumor activities investigation of a C-nucleoside analogue of ribavirin

European Journal of Medicinal Chemistry

Sabat, N.; Migianu-Griffoni, E.; Tudela, T.; Lecouvey, M.; Kellouche, S.; Carreiras, F.; Gallier, F.; Uziel, J.; Lubin-Germain, N.

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Enzymatic Formation of an Artificial Base Pair Using a Modified Adenine Nucleoside Triphosphate

Cleaved CD31 as a target for in vivo molecular imaging of inflammation.

Calls

Call

Deadline

Jan 2025

Application as permanent staff scientist at Institut Pasteur

Call

Deadline

Nov 2025

INCEPTION- Call for Workshop/Visiting Scientist

Events

15 Upcoming Events

Calendar

Today

28 Oct 2024

View all

conference

08:30

Oct 2024

3rd France – Japan symposium on HIV/AIDS & Infectious diseases basic research – Hugo Mouquet, Anavaj Sakuntabhai, Simon Cauchemez, Olivier Schwartz, Luis Romero Martín, Florian Dubois

Chemogenomic and Biological Screening Platform (PF-CCB)

UMR3523 – Chemistry for Life Sciences (Chem4Life)

phd

10:00

Nov 2024

PhD defense : Modern diet-induced microbiota alterations: impact on diseases susceptibility and transgenerational effects – Clara Delaroque – Clara Delaroque

Chemogenomic and Biological Screening Platform (PF-CCB)

UMR3523 – Chemistry for Life Sciences (Chem4Life)

seminar

10:00

Nov 2024

Neuroscience department seminar -Hiroshi Kohsaka : “Motor Circuits and Neuromechanics of Locomotion in Fruit Fly Larvae

Chemogenomic and Biological Screening Platform (PF-CCB)

UMR3523 – Chemistry for Life Sciences (Chem4Life)

conference

13:00

Nov 2024

Half-day “AI in structural biology: What’s next”

Chemogenomic and Biological Screening Platform (PF-CCB)

UMR3523 – Chemistry for Life Sciences (Chem4Life)

conference

09:00

Nov 2024

3rd Drug Discovery & Screening Symposium – “Innovative Therapeutics: Small Molecules and Biologics in Modern Medicine” – an ATC-DDS initiative

Chemogenomic and Biological Screening Platform (PF-CCB)

UMR3523 – Chemistry for Life Sciences (Chem4Life)

conference

09:20

Nov 2024

Symposium “Future of Parasitology 2024”

Chemogenomic and Biological Screening Platform (PF-CCB)

UMR3523 – Chemistry for Life Sciences (Chem4Life)

Jobs

Job: Post-doc

Network

INTERNATIONAL

Institutes

Projects

Publications

Cell reports. Medicine

Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies.

2021

Nature

Bacterial inhibition of Fas-mediated killing promotes neuroinvasion and persistence.

2022

Cerebral cortex (New York, N.Y. : 1991)

Polygenic Architecture of Human Neuroanatomical Diversity.

2020

BMC medicine

Transmissibility and pathogenicity of the emerging meningococcal serogroup W sequence type-11 complex South American strain: a mathematical modeling study.

2020

News

Annual Day of Microb’UP Institute 2025 – January 8th, 2025 – Odeon site

Oct 2024

News

Intragenomic conflicts with mobile genetic elements drive the evolution of natural tran...

Oct 2024

News

Phage-plasmids promote recombination and emergence of phages and plasmids

Oct 2024

News

Hijackers, hitchhikers, or co-drivers? The mysteries of mobilizable genetic elements

Oct 2024

A little guide for advanced search:

CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair.

Nature Communications

Lack of interaction between NEMO and SHARPIN impairs linear ubiquitination and NF-κB activation and leads to incontinentia pigmenti.

Journal of Allergy and Clinical Immunology

HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell

PLoS Pathogens

Interrogating RNA and protein spatial subcellular distribution in smFISH data with DypFISH

Cell Reports Methods

Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMPDHs.

Protein science : a publication of the Protein Society

A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy

ChemRxiv

A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors.

Antiviral research

Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation

Acta crystallographica. Section D, Biological crystallography

Interaction network among de novo purine nucleotide biosynthesis enzymes in Escherichia coli.

The FEBS journal

Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions

Synthesis

Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA.

Nature communications

The fully synthetic glycopeptide MAG-Tn3 therapeutic vaccine induces tumor-specific cytotoxic antibodies in breast cancer patients.

Cancer immunology, immunotherapy : CII

Synthesis of 2,6-Substituted-7-(Het)aryl-7-deazapurine Nucleobases (2,4-Disubstituted-5-(Het)aryl-pyrrolo[2,3-d]pyrimidines

Synthesis

An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis

Science Translational Medicine

Multigram synthesis of an orthogonally-protected pentasaccharide for use as a glycan precursor in a Shigella flexneri 3a conjugate vaccine: application to a ready-for-conjugation decasaccharide

Org. Chem. Front.

Synthesis and antitumor activities investigation of a C-nucleoside analogue of ribavirin

European Journal of Medicinal Chemistry

Calls

Application as permanent staff scientist at Institut Pasteur

INCEPTION- Call for Workshop/Visiting Scientist

Events

3rd France – Japan symposium on HIV/AIDS & Infectious diseases basic research – Hugo Mouquet, Anavaj Sakuntabhai, Simon Cauchemez, Olivier Schwartz, Luis Romero Martín, Florian Dubois

PhD defense : Modern diet-induced microbiota alterations: impact on diseases susceptibility and transgenerational effects – Clara Delaroque – Clara Delaroque

Neuroscience department seminar -Hiroshi Kohsaka : “Motor Circuits and Neuromechanics of Locomotion in Fruit Fly Larvae

Half-day “AI in structural biology: What’s next”

3rd Drug Discovery & Screening Symposium – “Innovative Therapeutics: Small Molecules and Biologics in Modern Medicine” – an ATC-DDS initiative

Symposium “Future of Parasitology 2024”

Jobs

Post-doctoral position in parasitology

Postdoctoral position in protein design at the Institut Pasteur

Postdoctoral position in inflammation /regeneration

Postdoc Position

Network

Publications

Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies.

Bacterial inhibition of Fas-mediated killing promotes neuroinvasion and persistence.

Polygenic Architecture of Human Neuroanatomical Diversity.

Transmissibility and pathogenicity of the emerging meningococcal serogroup W sequence type-11 complex South American strain: a mathematical modeling study.

News

Annual Day of Microb’UP Institute 2025 – January 8th, 2025 – Odeon site

Intragenomic conflicts with mobile genetic elements drive the evolution of natural tran...

Phage-plasmids promote recombination and emergence of phages and plasmids

Hijackers, hitchhikers, or co-drivers? The mysteries of mobilizable genetic elements