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© Pierre Gounon
Entrée de Listeria dans une cellule épithéliale (Grossissement X 10000). Image colorisée.
Publication : BMC systems biology

Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in BMC systems biology - 29 Jul 2013

Tchitchek N, Eisfeld AJ, Tisoncik-Go J, Josset L, Gralinski LE, Bécavin C, Tilton SC, Webb-Robertson BJ, Ferris MT, Totura AL, Li C, Neumann G, Metz TO, Smith RD, Waters KM, Baric R, Kawaoka Y, Katze MG

Link to Pubmed [PMID] – 23895213

BMC Syst Biol 2013;7:69

Influenza infection causes respiratory disease that can lead to death. The complex interplay between virus-encoded and host-specific pathogenicity regulators – and the relative contributions of each toward viral pathogenicity – is not well-understood.