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© Research
Publication : The American journal of tropical medicine and hygiene

Serum Aspergillus galactomannan for the management of disseminated histoplasmosis in AIDS.

Team: Fungal Biology and Pathogenicity
Team: Biology of infection
Member: Marc Lecuit
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in The American journal of tropical medicine and hygiene - 01 Aug 2012

Rivière S, Denis B, Bougnoux ME, Lanternier F, Lecuit M, Lortholary O,

Link to Pubmed [PMID] – 22855762

Link to DOI – 10.4269/ajtmh.2012.12-0119

Am J Trop Med Hyg 2012 Aug; 87(2): 303-5

Disseminated histoplasmosis is an emerging infection in patients with cellular immune deficiency in non-endemic countries, caused by the migration from endemic regions and the development of travels. Diagnosis can be challenging in this context because rapid diagnostic tools such as Histoplasma antigen detection or appropriate molecular tools are generally unavailable, serology is often negative in immunosuppressed patients, and isolation of the fungus from cultures often takes several weeks. Here, we report the contribution of galactomannan serum detection for the management of an HIV-infected patient with disseminated histoplasmosis.