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© Pierre Gounon
Entrée de Listeria dans une cellule épithéliale (Grossissement X 10000). Image colorisée.
Publication : Biochimica et biophysica acta

Phosphoinositides and host-pathogen interactions

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Biochimica et biophysica acta - 19 Sep 2014

Pizarro-Cerdá J, Kühbacher A, Cossart P

Link to Pubmed [PMID] – 25241942

Biochim. Biophys. Acta 2015 Jun;1851(6):911-8

Phosphoinositides control key cellular processes including vesicular trafficking and actin polymerization. Intracellular bacterial pathogens manipulate phosphoinositide metabolism in order to promote their uptake by target cells and to direct in some cases the biogenesis of their replication compartments. In this chapter, we review the molecular strategies that major pathogens including Listeria, Mycobacterium, Shigella, Salmonella, Legionella and Yersinia use to hijack phosphoinositides during infection. This article is part of a Special Issue entitled Phosphoinositides.

http://www.ncbi.nlm.nih.gov/pubmed/25241942