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Assistant Professor
Associate Professor
Clinical Research Assistant
Clinical Research Nurse
Clinician Researcher
Department Manager
Dual-education Student
Full Professor
Honorary Professor
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Master Student
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Nursing Staff
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
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Project Manager
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Research Engineer
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Technician
Undergraduate Student
Veterinary
Visiting Scientist

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Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

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JC Polyomavirus whole genome sequencing at the single molecule level reveals emerging neurotropic populations in Progressive Multifocal Leucoencephalopathy

Integrative Study of the Structural and Dynamical Properties of a KirBac3.1 Mutant: Functional Implication of a Highly Conserved Tryptophan in the Transmembrane Domain.

Coupe de Mycobacterium bovis ou bacille de Calmette et Guérin (BCG). Souche atténuée de bacille vivant, à l'origine du vaccin antituberculeux délivré par voie intradermique ou scarifications (Grossissement X 70000). Image colorisée.

Publication : Methods in molecular biology (Clifton, N.J.)

Mycolactone Purification from M. ulcerans Cultures and HPLC-Based Approaches for Mycolactone Quantification in Biological Samples.

Team: Immunobiology and Therapy

Member: Caroline Demangel

Member: Laure Guenin-Mace

Scientific Fields

Diseases

Organisms

Applications

Technique

Published in Methods in molecular biology (Clifton, N.J.) - 01 Jan 2022

Rifflet A, Demangel C, Guenin-Macé L,

Link to Pubmed [PMID] – 34643908

Link to DOI – 10.1007/978-1-0716-1779-3_13

Methods Mol Biol 2022 ; 2387(): 117-130

Mycolactones are a family of polyketide synthase products made by the human pathogen Mycobacterium ulcerans that were recently identified as novel inhibitors of the host membrane translocation complex (Sec61). Here, we provide protocols for the purification of mycolactones from bacterial cultures, and for their quantitative assessment in biological samples.

Published on: 01 Jan 2022 • Modified on: 19 Dec 2022