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© Pierre Gounon
Entrée de Listeria dans une cellule épithéliale (Grossissement X 10000). Image colorisée.
Publication : Microbes and infection / Institut Pasteur

Molecular mechanisms exploited by Listeria monocytogenes during host cell invasion

Team: Bacteria-Cell Interactions
Member: Pascale Cossart
Member: Javier Pizarro-Cerda
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Microbes and infection / Institut Pasteur - 07 May 2007

Seveau S, Pizarro-Cerda J, Cossart P

Link to Pubmed [PMID] – 17761447

Microbes Infect. 2007 Aug;9(10):1167-75

The facultative intracellular bacterial pathogen Listeria monocytogenes has evolved multiple strategies to invade a large panel of mammalian cells. Host cell invasion is critical for several stages of listeriosis pathology such as the initial crossing of the host intestinal barrier and the successive colonization of diverse target organs including the placenta. In this review, we address the main molecular mechanisms known to be used by L. monocytogenes during invasion of nonphagocytic cells and host tissues.