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© Therese Couderc, Marc Lecuit
Publication : Trends in microbiology

Making Sense of the Biodiversity and Virulence of Listeria monocytogenes.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Trends in microbiology - 11 Feb 2021

Disson O, Moura A, Lecuit M,

Link to Pubmed [PMID] – 33583696

Link to DOI – S0966-842X(21)00010-X10.1016/j.tim.2021.01.008

Trends Microbiol 2021 Feb; ():

Listeria monocytogenes is a foodborne pathogen responsible for listeriosis, an infection that can manifest in humans as bacteremia, meningoencephalitis in immunocompromised patients and the elderly, and fetal-placental infection in pregnant women. Reference strains from this facultative intracellular bacterium have been instrumental in the investigation of basic mechanisms in microbiology, immunology, and cell biology. The integration of bacterial population genomics with environmental, epidemiological, and clinical data allowed the uncovering of new factors involved in the virulence of L. monocytogenes and its adaptation to different environments. This review illustrates how these investigations have led to a better understanding of the bacterium’s virulence and the driving forces that shaped it.

https://pubmed.ncbi.nlm.nih.gov/33583696