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© Therese Couderc, Marc Lecuit
Publication : Journal of virology

Identification of the first human gyrovirus, a virus related to chicken anemia virus.

Team: Biology of infection
Team: Environment and Infectious Risks
Member: Marc Lecuit
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of virology - 01 Aug 2011

Sauvage V, Cheval J, Foulongne V, Gouilh MA, Pariente K, Manuguerra JC, Richardson J, Dereure O, Lecuit M, Burguiere A, Caro V, Eloit M,

Link to Pubmed [PMID] – 21632766

Link to DOI – 10.1128/JVI.00639-11

J Virol 2011 Aug; 85(15): 7948-50

We have identified in a skin swab sample from a healthy donor a new virus that we have named human gyrovirus (HGyV) because of its similarity to the chicken anemia virus (CAV), the only previously known member of the Gyrovirus genus. In particular, this virus encodes a homolog of the CAV apoptin, a protein that selectively induces apoptosis in cancer cells. By PCR screening, HGyV was found in 5 of 115 other nonlesional skin specimens but in 0 of 92 bronchoalveolar lavages or nasopharyngeal aspirates and in 0 of 92 fecal samples.