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© Research
Publication : Journal of theoretical biology

Modelling adipocytes size distribution

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of theoretical biology - 30 Apr 2013

Soula HA, Julienne H, Soulage CO, Géloën A

Link to Pubmed [PMID] – 23643531

J. Theor. Biol. 2013 Sep;332:89-95

Adipocytes are cells whose task is to store excess energy as lipid droplets in their cytoplasm. Adipocytes can adapt their size according to the lipid amount to be stored. Adipocyte size variation can reach one order of magnitude inside the same organism which is unique among cells. A striking feature in adipocytes size distribution is the lack of characteristic size since typical size distributions are bimodal. Since energy can be stored and retrieved and adipocytes are responsible for these lipid fluxes, we propose a simple model of size-dependent lipid fluxes that is able to predict typical adipocytes size distribution.

https://www.ncbi.nlm.nih.gov/pubmed/23643531